Is Nemifitide legal in the United States?

A lab made peptide for depression, given as a daily shot for 5 to 10 days. Three small studies between 2000 and 2006, in 52, 55 and 81 people, compared it with a dummy shot. The good results only show up when patients are sorted after the fact: by blood level, by one chosen moment, or by how severe their depression was. No study ever confirmed it, and work on it stopped.

Nemifitide is a lab made peptide of five amino acids. It is a changed copy of MIF-1, a small brain peptide.

How it works: In people, only two things were measured. A 1999 study reported a change in how blood platelets take up serotonin in treated patients.

Approval history: Not FDA approved. Work stopped after mid-stage studies. No study is registered on ClinicalTrials.gov, and we found no application for approval.

Approves prescription drugs, each for a named use. It also acts against unapproved products, including peptides sold online. Compounding pharmacies, which mix drugs to order, may make some compounds with a prescription. That only applies when the FDA puts the compound in a category of bulk ingredients it allows.

The legal category above is how The Longevity Archive reads U.S. Food and Drug Administration listings for Nemifitide on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check FDA directly

Whether Nemifitide is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United States. Before you compete or get tested, look up Nemifitide by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.