What is new, and what the evidence says
Every post cites its sources and links to the compound pages it covers. For learning only. No dosing advice.
Latest
Research / Sep 27, 2026 / 4 min read
2026 Mouse Lifespan Retest: Eight Compounds, No Gains
In 2026 the US mouse lifespan testing program retested astaxanthin, meclizine, mitoglitazone, pioglitazone, alpha-ketoglutarate, mifepristone, methotrexate and atorvastatin with telmisartan. None made mice live longer. What changed, and why dose and starting age matter.
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- Dispatch / Sep 12, 20268 min
Dispatch 001: Five Retatrutide Phase 3 Trials Have Finished And None Has Posted Results
- Metabolic / Sep 8, 20268 min
Tesofensine Is Not a Peptide: What It Is, the Trials, and the Heart-Rate Issue
- Longevity / Sep 8, 2026 / Long read12 min
Peptides for Longevity: What the Evidence Actually Shows in 2026
- Healing & Recovery / Sep 8, 20269 min
Peptides for Joint Pain: BPC-157, TB-500, Lorecivivint, Pentosan and Collagen Peptides, Evidence Tiered
- Healing & Recovery / Sep 8, 20268 min
Peptides for Gut Health: BPC-157, KPV and Larazotide Ranked by Human Evidence
- Metabolic / Sep 8, 2026 / Long read10 min
Oral GLP-1s in 2026: Wegovy Pill vs Foundayo (Orforglipron) vs Rybelsus, and What Is Coming
- Metabolic / Sep 8, 20269 min
MariTide (Maridebart Cafraglutide): The Once-Monthly GLP-1 Agonist and GIP Blocker, Explained
- Metabolic / Sep 8, 20269 min
Cagrilintide: The Amylin Half of CagriSema, and Why People Search 'Cagrilintide with Retatrutide'
- Longevity / Sep 8, 20269 min
Senolytics in 2026: Dasatinib plus Quercetin, Fisetin, and What Human Trials Have Shown
- Research / Sep 8, 20268 min
Peptides for Hair Growth: GHK-Cu, AHK-Cu, PTD-DBM and PP405
- Research / Sep 8, 20269 min
Peptides for Sleep: DSIP, Epitalon and Pinealon Against the Evidence
- Longevity / Sep 8, 20269 min
The Rapamycin Dosing Debate: What PEARL Tested, the Bioavailability Problem, and What Is Unproven
- Safety / Sep 8, 20269 min
Peptide Side Effects by Class: What Is Documented, What Is Anecdotal
- Safety / Sep 8, 20268 min
How to Read a Peptide Certificate of Analysis: HPLC Purity, Mass Spec Identity, Endotoxin, and Janoshik Verification
- Metabolic / Sep 8, 20267 min
SLU-PP-332 and 5-Amino-1MQ: Two 'Peptides' That Are Not Peptides, and What the Mouse Data Actually Show
- Metabolic / Sep 8, 20269 min
Retatrutide vs Tirzepatide vs Semaglutide vs the Pill: The 2026 GLP-1 Field Guide
- Longevity / Sep 8, 20268 min
NMN vs NR vs NAD+: The 2026 Head-to-Head Human Trials, and Who Funded the Comparisons
- Research / Sep 8, 2026 / Long read11 min
New Peptides and Longevity Compounds in 2026: What Is Actually New, What Is Newly Legal, and What Is Just New to Vendors
- Healing & Recovery / Sep 8, 20268 min
GLOW vs KLOW vs Wolverine: What Is in Each Stack and What the Evidence Says, Ingredient by Ingredient
- Longevity / Sep 8, 20267 min
SS-31 and Elamipretide: What the Forzinity Approval Does and Does Not Mean
- Metabolic / Sep 8, 20267 min
MOTS-c: The Mouse Data, the One Human Trial, and the 7 to 5 FDA Vote
- Longevity / Sep 8, 20268 min
Klotho Explained: Protein, Peptide, Gene Therapy or Supplement?
- Regulation / Sep 8, 20269 min
FDA Peptide Status in 2026: The Category 2 Removals, the July Votes, and What Actually Changed