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Legal status · Australia

Is Modified GRF 1-29 legal in Australia?

Written by Reviewed Sep 2026

Not approvedGrowth HormoneHuman studies cited: 2

Direct answer

No. Modified GRF 1-29 is not an approved medicine in Australia; its classification is "Not approved". Nothing containing it is authorized for any use in people. Vials labeled "for research use only" are not exempt: that label does not make human use lawful. On the evidence, 2 human studies are cited on its profile.

Modified GRF 1-29 in Australia at a glance

ClassificationNot approved
NoteNot on the ARTG. Prohibited in sport.
TGA approval statusNot approved by TGA
Human studies cited2 of 5 citations on the profile
ReviewedSep 2026

Classification and note come from the Modified GRF 1-29 profile, checked against Therapeutic Goods Administration (TGA) listings at the reviewed date.

What this means

  • 01

    No product containing Modified GRF 1-29 is approved by TGA for any use in Australia, so nothing on the market is authorized for people.

  • 02

    "Research use only" is a vendor label, not a legal category that permits human use. It does not exempt a product from medicines law.

  • 03

    Importing, supplying or promoting it for human use can fall under medicines legislation in Australia. This page is general information, not legal advice.

What Modified GRF 1-29 is

Sold as CJC-1295 without DAC, which is a contradiction: the DAC is what makes a molecule CJC-1295. The human trial everyone quotes, 2 to 10 fold higher growth hormone for 6 days or more with a half-life of 5.8 to 8.1 days, was run on the DAC form. No human trial of the version without the DAC has been located.

Start with the naming, because the naming is the error. The 2005 paper that created CJC-1295 tested three maleimido derivatives of human growth hormone releasing factor 1-29 designed to bond to the free thiol on cysteine 34 of serum albumin.

Mechanism: A growth hormone releasing hormone analogue acting at the GHRH receptor on anterior pituitary somatotrophs to trigger growth hormone release, which raises IGF-1 downstream. The tetrasubstitution of the native GRF 1-29 sequence resists dipeptidyl peptidase IV cleavage, extending the peptide's survival in plasma from minutes to somewhat longer, but it does not confer albumin binding.

Regulatory history: Not approved for any indication and not evaluated. Sermorelin, the unmodified GRF 1-29, was an approved medicine in the United States and is no longer marketed in its original form. Tesamorelin, a different GHRH analogue, is approved for HIV-associated lipodystrophy.

How TGA treats this kind of product

Registers or lists therapeutic goods on the ARTG and schedules substances in the Poisons Standard. Many peptides are Schedule 4 (prescription only), so possession without a prescription and personal importation are restricted even when no product is registered.

The classification above is the The Longevity Archive reading of Therapeutic Goods Administration listings for Modified GRF 1-29 at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.

Modified GRF 1-29 in other countries

Frequently asked questions

Is Modified GRF 1-29 legal in Australia?

No. Modified GRF 1-29 is not an approved medicine in Australia; its classification is "Not approved". Nothing containing it is authorized for any use in people. Vials labeled "for research use only" are not exempt: that label does not make human use lawful. On the evidence, 2 human studies are cited on its profile. Note: Not on the ARTG. Prohibited in sport.

Can I buy Modified GRF 1-29 in Australia?

No approved product exists to buy. In Australia Modified GRF 1-29 is classified as "Not approved", so there is no licensed pharmacy product. Vendors selling it "for research use only" are not selling it for human use, and that label does not change its legal status. This site does not list or recommend vendors. Note: Not on the ARTG. Prohibited in sport.

Is Modified GRF 1-29 TGA approved?

No. In Australia Modified GRF 1-29 is classified as "Not approved", which is not a TGA marketing approval. For comparison, the US FDA status is: Not approved for any indication and not evaluated. Sermorelin, the unmodified GRF 1-29, was an approved medicine in the United States and is no longer marketed in its original form. Tesamorelin, a different GHRH analogue, is approved for HIV-associated lipodystrophy.. On the evidence, 2 human studies are cited on its profile.

Related compounds in Australia

Full research profile

Mechanism, cited studies, FDA status and the full legal summary for Modified GRF 1-29 live on its compound profile.

Modified GRF 1-29 profile

This page is general information about the regulatory status of Modified GRF 1-29 in Australia, current as of Sep 2026. It is not legal advice, and classifications change; check Therapeutic Goods Administration directly or consult a lawyer for a specific situation. Educational use only. This database summarizes published research. It is not medical advice and contains no dosing protocols or recommendations for personal use. The Longevity Archive has no vendor relationships and does not recommend where to buy anything.