Peptide finder

What are you trying to change?

Pick as many as you like. The number on each one is how many people it has been measured in across the whole archive. So you can see where the evidence is before you choose.

1. 01Tesamorelin / IpamorelinBlendStrong. At least two finished studies in people, and at least 1,000 people who took it. 5 completed trials, 1,507 people given it.9 reported

   1,370 people3 studies1 found nothing

   • found nothingThe largest pile of evidence on either half of this blend, and it is for tesamorelin alone. Eight hundred and six patients were pooled from the two main trials. The deep fat around the organs fell on the drug and rose slightly on the dummy, a difference of about 15 percent. Fat just under the skin did not change, so...

     Journal of Clinical Endocrinology and Metabolism, 2010 · 806 people

   • Tesamorelin on its own shrank the deep fat around the organs in people with HIV. Four hundred and twelve patients took a 2 mg shot daily for six months, or a dummy shot. That fat fell by about 15 percent on the drug while it rose 5 percent on the dummy, and blood fats improved too. No ipamorelin was given. The dose...

     New England Journal of Medicine, 2007 · 412 people

   • A low dose of tesamorelin nudged thinking in the right direction in older adults. A hundred and fifty two people aged 55 to 87 took it or a dummy shot for five months, and sixty six of them already had mild memory trouble. The gain showed up mainly in planning and mental flexibility. IGF-1 more than doubled while...

     Archives of Neurology, 2012 · 152 people

2. 02TirzepatidePeptideStrong. At least two finished studies in people, and at least 1,000 people who took it. 9 completed trials, 22,802 people given it.11 reported

   751 people1 study

   • Tirzepatide beat semaglutide head to head, in a trial run by the company that sells tirzepatide. 751 adults with obesity and no diabetes took one drug or the other for 72 weeks. Everyone knew which they were getting. Tirzepatide took off 20.2% of body weight and semaglutide 13.7%. Waists shrank 18.4 cm against 13.0...

     New England Journal of Medicine, 2025 · 751 people

3. 03TesamorelinPeptideStrong. At least two finished studies in people, and at least 1,000 people who took it. 8 completed trials, 1,729 people given it.10 reported

   710 people5 studies1 found nothing

   • It worked on the deep fat around the organs, in the group it was designed for. 412 people with HIV who had gained fat around the middle took a daily tesamorelin injection or a dummy injection for six months. Nobody involved knew which. Deep belly fat fell about 15% on tesamorelin. In the dummy group it rose about 5%....

     New England Journal of Medicine, 2007 · 412 people

   • The fat stayed off while people kept injecting, and came back when they stopped. 273 people on tesamorelin and 137 on the dummy shot were reassigned at the halfway mark and followed to a year. Deep belly fat around the organs stayed about 18% down over the full year, and blood triglycerides stayed 51 mg/dL lower. Once...

     AIDS, 2008 · 137 people

   • found nothingTesamorelin did not improve thinking or memory, and this trial was too small to settle the question. 73 people with HIV and belly fat were assigned to the drug or to usual care for six months. Everybody knew who was getting it. Scores on the thinking tests came out the same in both groups. Waists did shrink 2.7 cm...

     Journal of Infectious Diseases, 2025 · 73 people

4. 04RetatrutidePeptideStrong. At least two finished studies in people, and at least 1,000 people who took it. 5 completed trials, 1,345 people given it.8 reported

   189 people1 study

   • Most of the weight lost was fat, on scans from a small slice of a larger trial. 189 people joined the scan study and only 103 had usable scans at both the start and week 36. Fat mass fell 26.1% and 23.2% at the two higher doses, against 4.5% on the dummy shot. The share of the loss that was muscle looked like what...

     The Lancet Diabetes & Endocrinology, 2025 · 189 people

5. 05SomatropinBiologicLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 84 people given it.9 reported

   84 people2 studies1 found nothing

   • Take growth hormone away from adults who need it and most things get worse. 60 adults with a pituitary shortage, treated for about ten years, were switched onto a dummy for four months. Their IGF-1 fell sharply. Two aspects of quality of life declined. Waists grew, deep belly fat rose, and cholesterol and an...

     Journal of Clinical Endocrinology and Metabolism, 2012 · 60 people

   • found nothingGrowth hormone changed what the body was made of without changing what the scales said. Twenty four adults whose bodies made too little growth hormone took it for six months, against others given a dummy version. They gained about 5.5 kg of muscle and lost about 5.7 kg of fat. Total weight barely moved, because the...

     New England Journal of Medicine, 1989 · 24 people

6. 06ForskolinSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 53 people given it.5 reported

   53 people2 studies1 found nothing

   • Body fat fell and testosterone rose, in thirty overweight men. The men all had a body mass index of 26 or above and took 250 mg of a 10 percent forskolin extract twice a day, or a dummy, decided by chance, for 12 weeks. Scans showed body fat percentage and fat mass dropped against the dummy group. Bone mass changed...

     Obesity Research, 2005 · 30 people

   • found nothingThe same supplement was tested in women and it did not work. 23 mildly overweight women took a 10 percent Coleus forskohlii extract twice a day or a dummy for 12 weeks, seven on the extract. Fat mass, lean mass and body fat percentage came out the same in both groups. Slight leanings toward less weight gain were too...

     Journal of the International Society of Sports Nutrition, 2005 · 23 people

7. 07SupaglutideBiologicModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 190 people given it.

   50 people1 study

   • The entire published obesity record for this drug is fifty people. They were spread across five doses and a dummy, starting at an average weight of 92.9 kg. Weight fell 7.16 percent against 0.86 percent on the dummy, and 82.5 percent of treated people lost at least a twentieth of their body weight, against nobody on...

     Diabetes, Obesity and Metabolism, 2026 · 50 people

8. 08HexarelinPeptideModerate. At least one finished study in people, and at least 100 people who took it. 6 completed trials, 105 people given it.7 reported

   21 people1 study

   • Body fat blunts the response, so the heavier you are the less hexarelin does. 21 healthy elderly people each got a single shot under the skin. The more fat someone carried, the lower their growth hormone peak, and fat mass predicted the response better than anything else measured. Being male or female made no...

     Clinical Endocrinology, 1998 · 21 people

9. 09TUDCASupplementLimited. People have taken it in a published study, but fewer than 100 of them. 3 completed trials, 54 people given it.7 reported

   20 people1 study1 found nothing

   • found nothingFour weeks of TUDCA improved insulin sensitivity in liver and muscle, and not in fat. 20 obese adults took 1,750 mg a day or a dummy for four weeks, with detailed infusion tests and samples from muscle and fat. Liver and muscle insulin sensitivity rose by roughly 30 percent while the dummy group did not change. The...

     Diabetes, 2010 · 20 people

10. 10Ursolic acidSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 16 people given it.6 reported

    16 people1 study1 found nothing

    • found nothingThe entire human record for ursolic acid is sixteen men. 16 healthy men averaging 29 did eight weeks of weight training, seven on training alone and nine also taking ursolic acid capsules three times a day. Body fat percentage fell in the supplemented group. Body weight, body mass index, muscle mass, blood sugar and...

      Korean Journal of Physiology and Pharmacology, 2014 · 16 people

11. 11ClenbuterolSmall moleculeLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 11 people given it.5 reported

    11 people1 study1 found nothing

    • found nothingClenbuterol does build muscle in people, and it wrecks your fitness while it does. 11 healthy young men took the drug for two weeks and a dummy for two weeks, in turn, with three weeks between. Lean mass rose by just under a kilogram. Fat mass did not move at all, which matters because fat loss is why most people buy...

      The Journal of Physiology, 2025 · 11 people

12. 12LeptinBiologicModerate. At least one finished study in people, and at least 100 people who took it. 6 completed trials, 844 people given it.5 reported

    3 people1 study

    • Give leptin to the rare children who have none and it transforms them. Three children born unable to make leptin were injected daily for up to four years. Appetite fell, fat mass fell, insulin and blood fats came back towards normal, and puberty arrived at the right age. Immune cells that had been depleted recovered...

      Journal of Clinical Investigation, 2002 · 3 people

13. 13ResveratrolSupplementModerate. At least one finished study in people, and at least 100 people who took it. 14 completed trials, 403 people given it.7 reported

    number of people not given2 studies2 found nothing

    • found nothingRun again at a high dose, the same idea produced nothing. Twenty-four obese but otherwise healthy men took high-dose resveratrol or a dummy pill for four weeks. The main measure was how well their bodies answered insulin, using the most exacting test there is. It drifted slightly worse in both groups. Blood pressure,...

      Diabetes, 2013 · number of people not given

    • found nothingResveratrol did not help fatty liver, and it may have irritated it. Twenty overweight men took 3,000 mg daily for eight weeks. Insulin resistance, liver fat, belly fat, blood fats and antioxidant activity were all unchanged, and so were the genes it was meant to act on. Two liver enzymes rose against the dummy, which...

      Clinical Gastroenterology and Hepatology, 2014 · number of people not given

14. 14MyostatinBiologicModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 188 people given it.

    number of people not given1 study

    • Blocking the receptor, not the hormone, caused big changes in body makeup. Adults with type 2 diabetes and obesity took bimagrumab or a dummy for 48 weeks. Fat fell by about a fifth, 7.5 kg, against almost nothing on the dummy. Muscle rose by 1.7 kg, waists shrank 9 cm, and average blood sugar fell by three quarters...

      JAMA Network Open, 2021 · number of people not given

15. 15KN069PeptideLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.

    number of people not given1 study

    • The first human data look promising, and they come from a very small, very early study. Chinese men with overweight or obesity were given single rising doses, three on the drug for every one on a dummy, plus a smaller repeat-dose group. Side effects were mostly mild stomach and bowel complaints. The drug clears...

      Diabetes, Obesity and Metabolism, 2026 · number of people not given

16. 16EcdysteroneSupplementModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 233 people given it.5 reported

    number of people not given1 study

    • 20 young men lifting weights took the plant extract or a dummy pill for twelve weeks. The extract group lost fat from the arms, legs and belly, and burned more fat. Their fasting insulin fell. But only the arm fat result was clearly better than the dummy pill group. Ten men per group is far too small to settle...

      Journal of Nutritional Science and Vitaminology, 2025 · number of people not given

17. 17MIB-626SupplementModerate. At least one finished study in people, and at least 100 people who took it. 4 completed trials, 107 people given it.1 reported

    number of people not given1 study1 found nothing

    • found nothingThe tablet moved some body measurements and left every measure of physical function untouched. 30 overweight or obese adults aged 45 and over took MIB-626 or a dummy tablet for four weeks. Weight fell by about two kilograms. Blood pressure and cholesterol both came down. Strength, stamina, how quickly muscles tired...

      Journal of Clinical Endocrinology and Metabolism, 2023 · number of people not given

18. 18TrevogrumabBiologicLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.3 reported

    number of people not given1 study

    • Blocking two muscle brakes at once protected most of the muscle people lose on semaglutide. With all three drugs, about 81% of the muscle normally lost was kept, and people lost about 27% more fat than on semaglutide alone. Two drugs instead of three kept about half. These are company-reported figures from a mid-stage...

      Regeneron press release, 2025 · number of people not given

19. 19HGH Fragment 176-191PeptideAnimal or lab only. Only animal or lab studies on this page. No study in people yet. 4 animal studies, no human study.5 reported

    number of people not given0 studies

    • In obese rats, the tail end of growth hormone copied growth hormone's fat burning in fat tissue and slowed weight gain, without blood sugar problems.

      Journal of Molecular Endocrinology, 2000 · number of people not given

    • In obese mice, 30 days of the growth hormone fragment by mouth slowed weight gain without changing how much they ate. In a dish, it also sped up fat breakdown in fat tissue taken from obese rodents and from people.

      American Journal of Physiology: Endocrinology and Metabolism, 2000 · number of people not given

20. 20TrodusquemineSmall moleculeAnimal or lab only. Only animal or lab studies on this page. No study in people yet. 2 animal studies, no human study.4 reported

    number of people not given0 studies

    • In fat mice on a rich diet. Weight loss came only from fat.

      Obesity, 2010 · number of people not given

21. 21GhrelinPeptideLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 27 people given it.1 reported

    number of people not given0 studies

    • In rats and mice. Ghrelin given into the body made them eat more and put on body fat.

      Nature, 2000 · number of people not given

22. 225-Amino-1MQSmall moleculeAnimal or lab only. Only animal or lab studies on this page. No study in people yet. 2 animal studies, no human study.6 reported

    number of people not given0 studies

    • In mice. Blockers of NNMT from the 5-amino-1MQ family cut body weight and fat in mice made fat on a high-fat diet.

      Biochemical Pharmacology, 2018 · number of people not given

23. 23E5 Plasma FractionProcedureAnimal or lab only. Only animal or lab studies on this page. No study in people yet. 4 animal studies, no human study.4 reported

    number of people not given0 studies

    • In mice, and this is the key comparison for this page. Half the plasma was swapped for salt water with 5 percent albumin, with no young plasma added at all. It matched or beat young blood on muscle repair, on fat and scarring in the liver, and on new brain cell growth. If simply thinning the blood does the same job,...

      Aging (Albany NY), 2020 · number of people not given

24. 24Plasma DilutionProcedureLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 42 people given it.6 reported

    number of people not given0 studies

    • In mice, half the plasma was swapped for salt water with 5 percent albumin. Nothing from a young animal was added. That single swap matched or beat joining a young and an old mouse together, on muscle repair, on fat and scarring in the liver, and on new brain cell growth in old mice. Comparing the proteins in mouse...

      Aging (Albany NY), 2020 · number of people not given