Is Adropin legal in the United States?

A peptide whose blood level is lower in people who are heavier and older. Every human study just measures it. No one has given adropin to a person, and the memory benefit that gets quoted was in ageing mice.

Adropin is made from the ENHO gene and floats in the blood at very low levels. It came out of mouse work suggesting a peptide needed for healthy metabolism and for stopping the insulin resistance that comes with obesity.

How it works: In animal work, adropin changes which fuel muscle burns, favouring sugar over fat. It also improves insulin sensitivity and the function of the blood vessel lining.

Approval history: Not a drug. Adropin is a peptide the body makes, measured in research studies. No adropin product is approved anywhere, and no trial giving it to people has been registered.

Approves prescription drugs, each for a named use. It also acts against unapproved products, including peptides sold online. Compounding pharmacies, which mix drugs to order, may make some compounds with a prescription. That only applies when the FDA puts the compound in a category of bulk ingredients it allows.

The legal category above is how The Longevity Archive reads U.S. Food and Drug Administration listings for Adropin on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check FDA directly

Whether Adropin is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United States. Before you compete or get tested, look up Adropin by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.