Is Magnesium legal in Australia?

The blood pressure effect is real and small, about 2 mmHg. The sleep evidence is three trials in 151 people rated low to very low certainty. The brain magnesium claim traces to rats, a retracted paper, and three trials all funded by the seller.

Magnesium is the supplement where the gap between marketing confidence and evidence quality is widest, and the useful thing about it is that the whole chain can be traced. What holds up: a lot of people eat less magnesium than the estimated average requirement, serum magnesium is a genuinely poor status marker because the body defends it at the expense of tissue stores, and supplementation lowers blood pressure by a small, real amount across 34 randomised trials.

Mechanism: Magnesium is a cofactor for more than 300 enzymes, including every reaction using ATP, since the physiological substrate is Mg-ATP. It is a natural calcium channel antagonist, which is the most plausible route to the blood pressure effect, and it modulates NMDA receptor activity, which is the basis of the neurological claims.

Regulatory history: Sold as a dietary supplement. Magnesium sulfate injection is a separately approved prescription drug for eclampsia and severe asthma, which is a different route, dose and purpose.

Registers or lists therapeutic goods on the ARTG and schedules substances in the Poisons Standard. Many peptides are Schedule 4 (prescription only), so possession without a prescription and personal importation are restricted even when no product is registered.

The classification above is the The Longevity Archive reading of Therapeutic Goods Administration listings for Magnesium at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.