Is Myostatin legal in Australia?

The brake on muscle growth. Knock it out in a mouse and you get a mouse twice as muscular, which launched a field. In primates the dominant brake turns out to be a different protein.

Myostatin is made by skeletal muscle and acts back on skeletal muscle to restrain its growth. It is a chalone, a signal whose job is to stop a tissue getting bigger.

Mechanism: Circulates as a latent disulfide-linked dimer held inactive by its own propeptide. Once activated it signals through activin type II receptors, principally ActRIIB, with type I receptors ALK4 and ALK5, through SMAD2 and SMAD3, to suppress muscle protein synthesis and satellite cell activity.

Regulatory history: Myostatin is an endogenous protein, not a drug. Drugs targeting the pathway are investigational; apitegromab has phase 3 data in spinal muscular atrophy.

Registers or lists therapeutic goods on the ARTG and schedules substances in the Poisons Standard. Many peptides are Schedule 4 (prescription only), so possession without a prescription and personal importation are restricted even when no product is registered.

The classification above is the The Longevity Archive reading of Therapeutic Goods Administration listings for Myostatin at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.