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Is NRPT legal?

Written by Reviewed Sep 2026

LongevityModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 176 people given it.
  • US: Sold as a supplement
  • UK: Sold as a supplement
  • AU: Available as a supplement / complementary medicine
  • CA: Sold as a supplement

The US comes first because most people ask about it. Each country has its own page. It names the agency, the law or rule, and what the legal category means in real life.

All four countries, side by side

What we listUnited States · FDAUnited Kingdom · MHRAAustralia · TGACanada · Health Canada
StatusNot approvedNot approvedNot approvedNot approved
Legal categorySold as a supplementSold as a supplementAvailable as a supplement / complementary medicineSold as a supplement
NoteSold as a dietary supplement. The published trials tested it as a supplement, not as a drug, and no health claim has been approved.Sold as a supplement. Nicotinamide riboside has been approved as a new food ingredient (novel food) in the EU and UK.Available as a complementary medicine. Not registered to treat anything.Sold as a natural health product. It has no approved health claim.
AgencyCheck FDA directlyCheck MHRA directlyCheck TGA directlyCheck Health Canada directly

US FDA status: Sold as a dietary supplement in the United States. Not approved as a drug for any use. Nicotinamide riboside chloride has new supplement ingredient safety filings with the FDA, and is generally recognised as safe for certain uses. Pterostilbene is also sold as a supplement ingredient.. Reviewed Sep 2026.

Country by country

Is NRPT legal in the United States?

NRPT can be sold in the United States as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. FDA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 3 completed human trials are cited on its profile.

The full United States answer

Is NRPT legal in the United Kingdom?

NRPT can be sold in the United Kingdom as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. MHRA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 3 completed human trials are cited on its profile.

The full United Kingdom answer

Is NRPT legal in Australia?

NRPT can be sold in Australia as a supplement or cosmetic ingredient. Its legal category is "Available as a supplement / complementary medicine". That is not approval as a drug. TGA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 3 completed human trials are cited on its profile.

The full Australia answer

Is NRPT legal in Canada?

NRPT can be sold in Canada as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. Health Canada has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 3 completed human trials are cited on its profile.

The full Canada answer

NRPT in sport and the military

Whether NRPT is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status. Before you compete or get tested, look up NRPT by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

The rules you compete or serve under decide this, not this page.

Related compounds

General information, current as of Sep 2026. Not legal advice. Legal status changes. For your own situation, check with the agency or a lawyer. Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use. Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.