Legal status · United States
Is Ursolic acid legal in the United States?
Written by Aaron CuhaReviewed Sep 2026
Direct answer
Ursolic acid can be sold in the United States as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. FDA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 1 completed human trial is cited on its profile.
- People given it
- 16
- Found nothing
- 1
Legal category
Sold as a supplement
FDA approval and compounding status, from the Ursolic acid profile.
Reviewed Sep 2026. This is a legal category, not legal advice.
A "research use only" label on a vial does not make it legal to use on people.
Ursolic acid in the United States at a glance
| Legal category | Sold as a supplement |
|---|---|
| FDA approval status | Sold as a dietary supplement. Not an approved drug and not approved to prevent or treat anything. |
| Studies in people | 1 of 2 sources on the profile |
| Reviewed | Sep 2026 |
The legal category and note come from the Ursolic acid profile. We checked them against U.S. Food and Drug Administration (FDA) listings on the reviewed date.
What this means
- 01
Ursolic acid can be sold in the United States as a supplement, food or cosmetic ingredient, under the legal category above. It has no approval as a drug.
- 02
Being sold as a supplement means FDA has not checked any health claim. The makers are responsible for safety and labels, and quality varies from product to product.
- 03
Versions you inject, and "research use only" versions, are not supplements. That label does not make them legal to use in people, and anything you inject falls under the rules for medicines.
What Ursolic acid is
It did not change lifespan at the dose tested in mice, in the same test where acarbose made male mice live 16 to 17 percent longer. The whole human record is one eight-week study in 16 men. Body fat percentage went down. Lean tissue, like muscle, did not change.
Ursolic acid is a plant compound found in apple peel, rosemary and holy basil. It is sold almost entirely because of one line of mouse studies from a single lab.
How it works: It is a plant compound from a family called triterpenoids. The muscle idea comes from lab work suggesting it boosts insulin and IGF-1 signals in muscle.
Approval history: Sold as a dietary supplement. Not an approved drug and not approved to prevent or treat anything.
How FDA treats this kind of product
Approves prescription drugs, each for a named use. It also acts against unapproved products, including peptides sold online. Compounding pharmacies, which mix drugs to order, may make some compounds with a prescription. That only applies when the FDA puts the compound in a category of bulk ingredients it allows.
The legal category above is how The Longevity Archive reads U.S. Food and Drug Administration listings for Ursolic acid on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.
Ursolic acid in sport and the military
Whether Ursolic acid is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United States. Before you compete or get tested, look up Ursolic acid by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.
- WADA Prohibited List
- Global DRO (check a named product)
- USADA (US athletes)
- Operation Supplement Safety (US service members)
The rules you compete or serve under decide this, not this page.
Ursolic acid in other countries
Frequently asked questions
Is Ursolic acid legal in the United States?
Ursolic acid can be sold in the United States as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. FDA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 1 completed human trial is cited on its profile.
Can I buy Ursolic acid in the United States?
Yes, as a supplement or cosmetic. In the United States, Ursolic acid has the legal category "Sold as a supplement". So products you swallow, put on your skin or use as a cosmetic can be sold under supplement rules. Versions you inject, and products labeled "research use only", are not supplements. They are not approved for use in people.
Is Ursolic acid FDA approved?
No. FDA status: Sold as a dietary supplement. Not an approved drug and not approved to prevent or treat anything.. Current US legal category: "Sold as a supplement". On the evidence, 1 completed human trial is cited on its profile.
Related compounds in the United States
Full research profile
How Ursolic acid works, the studies we cite, FDA status and the full legal summary are all on its compound profile.
Ursolic acid profileThis page is general information about the legal status of Ursolic acid in the United States, current as of Sep 2026. It is not legal advice. Legal status changes. For your own situation, check with U.S. Food and Drug Administration or ask a lawyer. Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use. Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.