Is 17-alpha-estradiol legal in Australia?

One of the most reliably replicated lifespan extenders in mice, robust at higher doses and even when started late in life. It does not work in females, and nobody knows why.

This is among the strongest pharmacological lifespan results in existence, and it comes with a caveat so large that most coverage simply omits it. 17-alpha-estradiol is the mirror-image stereoisomer of the main human estrogen.

Mechanism: The stereoisomer of 17-beta-estradiol at carbon 17, which drops its affinity for classical estrogen receptors by orders of magnitude and removes the feminising activity. Because it is not acting as a conventional estrogen, the mechanism behind its lifespan effect is genuinely unresolved.

Regulatory history: Not approved in the United States for any indication. Marketed in some European countries as a topical preparation for androgenetic alopecia, which is a different use, route and dose from the lifespan work.

Registers or lists therapeutic goods on the ARTG and schedules substances in the Poisons Standard. Many peptides are Schedule 4 (prescription only), so possession without a prescription and personal importation are restricted even when no product is registered.

The classification above is the The Longevity Archive reading of Therapeutic Goods Administration listings for 17-alpha-estradiol at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.