Is Mitoglitazone legal in Australia?

In people, it was tested in 356 people with type 2 diabetes and 29 people with Alzheimer disease. The company ran both studies, and no large final-stage study followed. In male mice started at 7 months, typical lifespan rose 8.7 percent. A retest started at 18 months failed, and female mice died sooner.

Mitoglitazone is a diabetes drug from the same family as pioglitazone. It was built to keep pioglitazone's effect on insulin while avoiding its main downsides, water retention and weight gain.

How it works: Mitoglitazone sticks to the pyruvate carrier, a two-part gate (MPC1 and MPC2) that lets pyruvate into mitochondria. A lab method that chemically tags what a drug touches found this gate is where drugs in this family bind inside mitochondria.

Approval history: Investigational, not approved. Mid-stage studies in type 2 diabetes (2011) and Alzheimer disease (2013) finished, with results posted. No final-stage study registered. The longer lifespan was in male mice started on it at 7 months old. A repeat test started at 18 months found no benefit in males and shorter lives in females.

Registers or lists medicines and health products on the ARTG, its official register. It also sorts substances into schedules in the Poisons Standard. Many peptides are Schedule 4 (prescription only). So having them without a prescription, or importing them for yourself, is restricted. That is true even when no product is registered.

The legal category above is how The Longevity Archive reads Therapeutic Goods Administration listings for Mitoglitazone on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check TGA directly

Whether Mitoglitazone is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in Australia. Before you compete or get tested, look up Mitoglitazone by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.