Is NAD+ / B Complex legal in the United Kingdom?

Injectable NAD+ blended with B12 and sometimes B6, sold as a clinic drip or a subcutaneous vial. No study has tested the combination. By mass the B12 is a rounding error: at a typical 500 mg NAD+ drip with a 1,000 microgram B12 add-on, the B12 is about 0.2 percent of the active ingredient, roughly one B12 molecule for every thousand NAD+ molecules. The one placebo-controlled trial of an intravenous vitamin cocktail found no significant difference from lactated Ringer's on any outcome.

Start with the same point that governs every NAD page on this site. Raising a number in blood is easy to demonstrate.

Mechanism: NAD+ is a redox coenzyme and the substrate for sirtuins, PARPs and CD38. Tissue levels decline with age, which is the entire basis of the marketing.

Regulatory history: Not approved as a blend. Injectable B12 is approved for deficiency; NAD+ is not an approved drug and reaches patients through compounding and IV clinics.

Licenses medicines for the UK market. A compound without a marketing authorisation is an unlicensed medicine, which can only lawfully be supplied for human use through a prescriber under the specials scheme, not sold as a research product.

The classification above is the The Longevity Archive reading of Medicines and Healthcare products Regulatory Agency listings for NAD+ / B Complex at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.