Legal status by country
Is NDGA legal?
Written by Aaron CuhaReviewed Sep 2026
How NDGA is classified in the United States, United Kingdom, Australia and Canada, side by side. Each country has its own page with a direct answer, the regulator's approval status and what the classification means in practice.
All four countries, side by side
| Attribute | United States · FDA | United Kingdom · MHRA | Australia · TGA | Canada · Health Canada |
|---|---|---|---|---|
| Status | Not approved | Not approved | Not approved | Not approved |
| Classification | Not approved; research use only | Not licensed | Not approved | Not approved |
| Note | No systemic approval. The related herbal product chaparral has been associated with serious liver injury and subject to regulatory warning. A topical formulation held an approval for a skin condition. | None recorded | None recorded | None recorded |
US FDA status: Not approved for any systemic indication. Masoprocol, a topical formulation, held an approval for actinic keratoses. Chaparral, the herbal product from the same plant, has been the subject of regulatory warnings over liver injury.. Reviewed Sep 2026.
Related compounds
General information current as of Sep 2026, not legal advice. Classifications change; confirm with the regulator or a lawyer for a specific situation. Educational use only. This database summarizes published research. It is not medical advice and contains no dosing protocols or recommendations for personal use. The Longevity Archive has no vendor relationships.