Is Oxyntomodulin legal in the United States?

Oxyntomodulin is glucagon with eight extra building blocks on the end. That tail lets it weakly switch on two hormone receptors at once, glucagon's and GLP-1's. It is the natural model for every drug that hits both.

Oxyntomodulin is the glucagon molecule plus a tail of eight building blocks. That one fact explains what it does and why it is on this site.

How it works: It weakly switches on two receptors, glucagon's and GLP-1's, and has none of its own. The idea behind the pair is that GLP-1 turns down appetite while glucagon raises how much energy you burn.

Approval history: Not approved and not sold anywhere. It matters to medicine as a model for designing new drugs.

Approves prescription drugs, each for a named use. It also acts against unapproved products, including peptides sold online. Compounding pharmacies, which mix drugs to order, may make some compounds with a prescription. That only applies when the FDA puts the compound in a category of bulk ingredients it allows.

The legal category above is how The Longevity Archive reads U.S. Food and Drug Administration listings for Oxyntomodulin on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check FDA directly

Whether Oxyntomodulin is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United States. Before you compete or get tested, look up Oxyntomodulin by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.