Legal status · United Kingdom
Is PQQ legal in the United Kingdom?
Written by Aaron CuhaReviewed Sep 2026
Direct answer
PQQ can be sold in the United Kingdom as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. MHRA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 3 completed human trials are cited on its profile.
- People given it
- 116
- Found nothing
- 2
Legal category
Sold as a supplement
Sold as a food supplement.
Reviewed Sep 2026. This is a legal category, not legal advice.
A "research use only" label on a vial does not make it legal to use on people.
PQQ in the United Kingdom at a glance
| Legal category | Sold as a supplement |
|---|---|
| Note | Sold as a food supplement. |
| MHRA approval status | Not approved by MHRA as a drug; sold as a supplement or cosmetic |
| Studies in people | 4 of 6 sources on the profile |
| Reviewed | Sep 2026 |
The legal category and note come from the PQQ profile. We checked them against Medicines and Healthcare products Regulatory Agency (MHRA) listings on the reviewed date.
What this means
- 01
PQQ can be sold in the United Kingdom as a supplement, food or cosmetic ingredient, under the legal category above. It has no approval as a drug.
- 02
Being sold as a supplement means MHRA has not checked any health claim. The makers are responsible for safety and labels, and quality varies from product to product.
- 03
Versions you inject, and "research use only" versions, are not supplements. That label does not make them legal to use in people, and anything you inject falls under the rules for medicines.
What PQQ is
Sold to grow new mitochondria, the cell's power plants. In a six-week training study, PQQ raised one mitochondria-building protein more than a dummy pill did, but did nothing for fitness. A study in human skin cells found no new mitochondria at all.
PQQ is a small molecule found in tiny amounts in food and sold as a supplement, usually as a salt called PQQ disodium. The sales claim is specific and testable: that it grows new mitochondria by switching on a master protein called PGC-1alpha.
How it works: PQQ flips back and forth between two chemical states. That lets it act as an antioxidant and as a signal inside cells.
Approval history: Sold as a dietary supplement in the United States. Not an approved drug for any use, anywhere.
How MHRA treats this kind of product
Licenses medicines for sale in the UK. A compound without a licence to be sold (a marketing authorisation) is an unlicensed medicine. The law only lets it reach people through a prescriber, under the specials scheme (unlicensed medicines made for one patient's needs). It cannot be sold as a research product.
The legal category above is how The Longevity Archive reads Medicines and Healthcare products Regulatory Agency listings for PQQ on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.
PQQ in sport and the military
Whether PQQ is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United Kingdom. Before you compete or get tested, look up PQQ by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.
- WADA Prohibited List
- Global DRO (check a named product)
- USADA (US athletes)
- Operation Supplement Safety (US service members)
The rules you compete or serve under decide this, not this page.
PQQ in other countries
Frequently asked questions
Is PQQ legal in the United Kingdom?
PQQ can be sold in the United Kingdom as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. MHRA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, 3 completed human trials are cited on its profile. Note: Sold as a food supplement.
Can I buy PQQ in the United Kingdom?
Yes, as a supplement or cosmetic. In the United Kingdom, PQQ has the legal category "Sold as a supplement". So products you swallow, put on your skin or use as a cosmetic can be sold under supplement rules. Versions you inject, and products labeled "research use only", are not supplements. They are not approved for use in people. Note: Sold as a food supplement.
Is PQQ MHRA approved?
No. In the United Kingdom, PQQ has the legal category "Sold as a supplement". That is not a MHRA approval to sell it. For comparison, its US FDA status is: Sold as a dietary supplement in the United States. Not an approved drug for any use, anywhere.. On the evidence, 3 completed human trials are cited on its profile.
Related compounds in the United Kingdom
Full research profile
How PQQ works, the studies we cite, FDA status and the full legal summary are all on its compound profile.
PQQ profileThis page is general information about the legal status of PQQ in the United Kingdom, current as of Sep 2026. It is not legal advice. Legal status changes. For your own situation, check with Medicines and Healthcare products Regulatory Agency or ask a lawyer. Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use. Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.