Is Tesamorelin / Ipamorelin legal in the United States?

The clinic version of the growth hormone blend. It pairs tesamorelin, a GHRH copy with FDA approval and results from 806 patients in large final-stage trials, with ipamorelin, whose one human trial missed its goal. No study has tested the two together. On the common 5 mg plus 5 mg vial, getting the 2 mg tesamorelin dose behind the approved result also gives you 2 mg of ipamorelin. That is roughly seven to ten times the dose ipamorelin is used at alone.

This is the blend that gets prescribed, rather than shipped in a plain box. It is also the one with the widest gap between the evidence for each part and the evidence for the blend.

How it works: Tesamorelin presses the GHRH switch in the pituitary. That makes the body's own growth hormone bursts bigger, while the brain's feedback checks stay in place.

Approval history: Not approved as a blend. Tesamorelin alone is FDA-approved as Egrifta, for the shifted body fat some people with HIV get. Ipamorelin is not approved, and no combination product exists.

Approves prescription drugs, each for a named use. It also acts against unapproved products, including peptides sold online. Compounding pharmacies, which mix drugs to order, may make some compounds with a prescription. That only applies when the FDA puts the compound in a category of bulk ingredients it allows.

The legal category above is how The Longevity Archive reads U.S. Food and Drug Administration listings for Tesamorelin / Ipamorelin on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check FDA directly

Whether Tesamorelin / Ipamorelin is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United States. Before you compete or get tested, look up Tesamorelin / Ipamorelin by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.