Is Beta-2 Microglobulin legal in Australia?

A blood protein that rises with age. Injected into young mice, it harms new brain cell growth and memory. In people it is a long-standing hospital blood test and goes with worse thinking scores. Nobody has tried lowering it for ageing.

The human evidence is from watching, not treating. A 2025 analysis looked at 1,267 US adults aged 60 and over from a national health survey run between 1999 and 2002.

How it works: In mice, B2M given into the body or straight into the memory centre harms memory and new brain cell growth. The harm is partly reduced in mice with less of the immune-display molecule on their cell surfaces.

Approval history: No therapy that lowers B2M is approved for ageing or thinking skills, and none is in a registered study for those uses. Doctors measure B2M in lab tests for kidney and blood diseases.

Registers or lists medicines and health products on the ARTG, its official register. It also sorts substances into schedules in the Poisons Standard. Many peptides are Schedule 4 (prescription only). So having them without a prescription, or importing them for yourself, is restricted. That is true even when no product is registered.

The legal category above is how The Longevity Archive reads Therapeutic Goods Administration listings for Beta-2 Microglobulin on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check TGA directly

Whether Beta-2 Microglobulin is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in Australia. Before you compete or get tested, look up Beta-2 Microglobulin by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.