Is BIO101 legal in the United Kingdom?

A 233-person phase 2b in sarcopenia that missed its primary endpoint in the full analysis set and hit it per-protocol, with COVID-19 destroying 55 percent of its final assessments.

BIO101 is the pharmaceutical development of the same molecule sold as an ecdysterone supplement, and its trial is the most informative thing on any of these three pages. 5, to two BIO101 doses or placebo for six to nine months.

Mechanism: Pharmaceutical-grade 20-hydroxyecdysone, developed as an activator of the MAS receptor, the receptor for angiotensin 1-7 and part of the protective counter-regulatory arm of the renin-angiotensin system. Activating that arm opposes the muscle wasting, fibrosis and inflammation driven by angiotensin II signalling through the AT1 receptor.

Regulatory history: Investigational. Not approved for any indication. No pharmaceutical treatment for sarcopenia exists anywhere.

Licenses medicines for the UK market. A compound without a marketing authorisation is an unlicensed medicine, which can only lawfully be supplied for human use through a prescriber under the specials scheme, not sold as a research product.

The classification above is the The Longevity Archive reading of Medicines and Healthcare products Regulatory Agency listings for BIO101 at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.