Is GIP legal in the United Kingdom?

One of your two incretin hormones, and the parent ligand of every dual and triple agonist on this site. Both blocking it and activating it produce weight loss in humans, which nobody has resolved.

GIP is one of the two mammalian incretins. It is released by K cells in the upper small intestine when you eat and it amplifies the insulin your pancreas puts out in response to glucose.

Mechanism: Binds GIPR, a class B1 secretin-family G protein-coupled receptor that is canonically Gs-coupled and raises cAMP. In the pancreatic beta cell that potentiates glucose-stimulated insulin secretion, which is glucose-dependent, so GIP does not drive insulin release when glucose is normal.

Regulatory history: Not an approved drug and not in clinical use as a therapeutic. Drugs acting at its receptor are approved, including tirzepatide.

Licenses medicines for the UK market. A compound without a marketing authorisation is an unlicensed medicine, which can only lawfully be supplied for human use through a prescriber under the specials scheme, not sold as a research product.

The classification above is the The Longevity Archive reading of Medicines and Healthcare products Regulatory Agency listings for GIP at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.