Is OSKM Cyclic Partial Reprogramming legal in Australia?

All four Yamanaka genes, switched on in short bursts. It made a mouse bred to age too fast live longer, not a normal mouse. The same move in living mice causes tumours, including in the kidney.

Nobody has been given OSKM. There is no registered trial of four-gene reprogramming in people anywhere.

How it works: Shown in mice only. Short bursts of Oct4, Sox2, Klf4 and c-Myc push cells part way back toward being stem cells.

Approval history: Not approved anywhere. ClinicalTrials.gov lists no human study of OSKM reprogramming, which uses four genes. The only registered human reprogramming study uses the three-gene OSK set.

Registers or lists medicines and health products on the ARTG, its official register. It also sorts substances into schedules in the Poisons Standard. Many peptides are Schedule 4 (prescription only). So having them without a prescription, or importing them for yourself, is restricted. That is true even when no product is registered.

The legal category above is how The Longevity Archive reads Therapeutic Goods Administration listings for OSKM Cyclic Partial Reprogramming on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check TGA directly

Whether OSKM Cyclic Partial Reprogramming is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in Australia. Before you compete or get tested, look up OSKM Cyclic Partial Reprogramming by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.