CJC-1295 with GHRP-2 dosage and evidence
Written by Aaron CuhaReviewed Sep 2026
The short answer
CJC-1295 with GHRP-2 is a 10 mg vial split evenly between two kinds of growth hormone booster.
Evidence grade for CJC-1295 with GHRP-2: Limited. The rule: people have taken it in a published study, but fewer than 100 of them. The sum on this page: 2 completed trials, none stating how many people. A grade counts how much has been done to people, not whether it works.
- People given it
- 0
- Human studies
- 2
- Found nothing
- 0
Dose
No human dose established
Amounts that were given in studies sit in Human evidence on this page. None of them is a personal dose.
2 completed trials, 0 people given it
8 effects reported, 5 unwanted, 3 wanted, by people using it, not a trial
Goal pages: Fat loss and metabolism, Hormones and growth hormone
In plain English
In plain English, from Aaron
This is how I would explain it to a friend. The evidence, with the numbers, is further down the page.
Two growth hormone peptides in one 10 mg vial, 5 mg of each. One raises the size of a growth hormone pulse. The other sets a pulse off. They hit two different switches, which is the real reason people pair them. Nobody has tested this vial.
What people take it for
- Better sleep.
- Losing fat and holding muscle.
- Healing faster.
- Feeling younger.
What studies in people showed
The two drug types have been tested together in people, and it worked. In healthy older adults, running a GHRP with GHRH for 24 hours pushed growth hormone higher than GHRH alone. The boost was three times bigger in young volunteers than older ones, and 2.3 times bigger in older women than older men. Thirty days of the GHRP alone kept growth hormone more than 1.8 times higher at day 14 and day 30. That study used drips in a clinic. It is not this vial. Now the part that trips people up. Here are the famous numbers for CJC-1295. A 2 to 10 times growth hormone rise, for six days or more. A half life of 5.8 to 8.1 days. Those belong to the long acting version. Most vials labelled no DAC hold a different molecule that is gone in minutes. If you quote the six day number for a no DAC vial you are out by a mile. The math: mix 10 mg with 2 mL and every unit mark carries 25 micrograms of each. A 4 unit draw is 100 micrograms of each.
What people report
Reports, not study results
The good
- Deeper sleep in the first two weeks. This is the most common report in the whole category.
- Vivid dreams.
- Feeling better recovered from training after a month or two.
The bad
- Strong hunger. That is not a rumour. A study with a dummy group showed this peptide raises food intake in healthy men.
- Water retention, puffy hands and tingling fingers.
- A hot flushed face for a few minutes after the shot.
- Nothing on the scale or in the mirror after a full cycle, which is common.
- You cannot turn the hunger down without turning the other half down too.
Where these come from: Peptide and gym forums, clinic write-ups and seller pages. The hunger is the one thing here that also shows up in a proper human study, which is listed on this page.
My bottom line
The two switch idea is real and has been shown to work in a clinic. Your vial is not that study, and the molecule in it may not even be the one on the label.
An opinion, not a finding. I am a coach, not a doctor.
What it has been measured to do
Measured in people
Goals CJC-1295 with GHRP-2 has been tested for in people, biggest studies first. We count only what the studies on this page say, so the real numbers may be higher.
- Growth hormone and IGF-1no headcount stated · 1 study
- Feeling less hungryno headcount stated · 1 study
What people using it report
Real people telling you what happened to them. Nobody checked it, and the people who post are not a fair sample, so it cannot prove anything works. It is still the best guide on this page to what people actually do with CJC-1295 with GHRP-2, what they expect, and what goes wrong. The full account, including the negative reports, is below.
34 of the 36 indexed goals have no study of any kind behind CJC-1295 with GHRP-2
No study in people, animals or cells on this page reports a result for these. That does not prove CJC-1295 with GHRP-2 does nothing for them. It does mean anything you have heard about CJC-1295 with GHRP-2 and one of these did not come from a study cited here.
Show full evidence
What is CJC-1295 with GHRP-2?
CJC-1295 with GHRP-2 is a 10 mg vial split evenly between two kinds of growth hormone booster. One copies GHRH, the brain's own growth hormone switch. The other works on the hunger hormone's receptor. Pairing these two kinds has real data in people. In one study, the pair pushed growth hormone higher than either one alone. But that study used different drugs, given by drip or pump, in a clinic. No study has tested this vial.
This is the oldest idea in the growth hormone part of the peptide market. Push the gland that makes growth hormone from two sides at once. The GHRH copy makes each burst of growth hormone bigger. The hunger hormone copy sets off a burst and blocks the body's brake on growth hormone. Together they do more than either one. Sellers did not make this idea up. It has been tested, and it held.
But what was tested was not this product. In healthy older adults, a 24 hour drip under the skin of GHRP-2 plus GHRH pushed out more growth hormone than GHRH alone. The boost from pairing them was three times bigger in young people than in older ones. It was 2.3 times bigger in older women than older men. Thirty days of nonstop GHRP-2 raised growth hormone bursts more than three times on day one. They were still up more than 1.8 times at days 14 and 30. IGF-1, the growth factor growth hormone makes, held steady at its new level. That was a clinic study with pumps and drips. It used GHRH itself, not a long-acting copy. It backs the idea. It does not describe a nightly shot from a 5 plus 5 vial.
The math. Ten milligrams, 5 mg of each, mixed with 2 mL of water. Each mL holds 5 mg of powder, or 2.5 mg of each peptide. One mark on a 100 unit insulin syringe is 25 micrograms of each. A 4 unit draw is 100 micrograms of each. That is the amount people say they use when they take either one alone.
The first real problem is what is in the vial. Most of what is sold as CJC-1295 without DAC is mod GRF 1-29. That is a different molecule from the CJC-1295 in the published study. In that study, single shots raised growth hormone two to ten times for six days or more. They raised IGF-1 for nine to eleven days. Half the drug was still in the body after 5.8 to 8.1 days. Those numbers belong to the version with DAC, which lasts days. The version in these vials lasts minutes. Quoting the long numbers for a vial without the long-acting molecule is the most common mistake here.
The second problem is the choice of GHRP. GHRP-2 makes you hungry. In healthy men it made them eat more, the same way the hunger hormone does. That helps someone who is underweight. It is a problem for someone trying to lose fat. A fixed blend gives you no way to cut the GHRP and keep the GHRH half.
How does CJC-1295 with GHRP-2 work?
Two switches, one system. The GHRH copy presses the GHRH switch on the growth hormone cells in the pituitary gland, and makes each burst of growth hormone bigger. GHRP-2 presses the hunger hormone switch on the same cells. That sets off a burst and pushes against the body's brake on growth hormone. Both roads end at growth hormone and then IGF-1. So any change in blood IGF-1 belongs to the pair. You cannot tell which half caused it.
What have studies in people found about CJC-1295 with GHRP-2?
People have been given these two kinds of drugs together, and the pair worked on growth hormone. This product has not been studied. It uses different molecules, given a different way, in a different setting.
- The pairing of the two drug kinds: in healthy older adults, a 24 hour drip of GHRP-2 plus GHRH raised growth hormone more than either one alone. The boost was bigger in young people and in women.
- GHRP-2 alone: 30 days of nonstop drip kept growth hormone raised, with IGF-1 steady at its new level. Safety blood tests stayed normal.
- GHRP-2 makes healthy men eat more.
- CJC-1295 with DAC: single shots raised growth hormone two to ten times for six days or more, and IGF-1 for nine to eleven days. Half the drug was gone after 5.8 to 8.1 days.
- This vial: no published study and no listed trial.
What this does not tell you: Every one of those results is a blood number, not a real-life result. Growth hormone and IGF-1 went up. No study of either peptide has measured what people buy them for: muscle and fat over a year, healing from injury, or how anyone ages. And the pairing result used a GHRH drip, not a long-acting copy from a vial.
What do people who took CJC-1295 with GHRP-2 report?
This is what real people say happened to them, good and bad. Nobody measured it. A report cannot tell a real effect from the lift people get just from expecting it to work, from a diet or training change made at the same time, or from what was really in the vial. We still put it near the top. It is the next best thing to a study in people: what happens when real people use it, including what goes wrong.
- Deeper sleep in the first two weeks. This is the most steady report for this whole group of products.
- Vivid dreams along with the sleep change.
- Strong hunger. This comes from GHRP-2 and is the usual reason people switch to ipamorelin.
- Water retention, tingling hands and some joint aches. This is the classic pattern of too much growth hormone.
- Flushing and a warm face for a few minutes after the shot.
- Nothing you can measure on the scale or in the mirror after a full cycle. This is common.
Sources: Peptide and bodybuilding forums including r/peptides, clinic write-ups and vendor pages. The appetite effect is also documented in the controlled study cited above, which is the rare case where a forum report and a trial finding agree.
The state of the research
What is really in the vial matters more than people think. The real CJC-1295 is a GHRH copy with DAC attached, which is what makes it last for days. Most vials labelled CJC-1295 no DAC hold mod GRF 1-29, which works for minutes. The numbers people quote on forums belong to the first molecule. A buyer who expects six days of raised growth hormone from a vial of the second molecule is off by hundreds of times.
Second, and plainly: raising IGF-1 is not a result by itself. It is a blood number that stands in for the results people want. No study has shown this kind of drug does the things it is sold for. The blood number can go up while the thing you care about does not move at all.
The evidence, in charts
Fig. 1a · how many people
3studies in people cited, but none says how many people took part
number of people not stated
We do not draw a total, because none of the studies in people on this page gives one. Read the sources below for what each study measured.
We read the number of people from the source lines on this page. Where a line gives no number, we count nothing for it. We do not guess.
Fig. 1b · evidence mix
3 of 4 sources here are studies in people. The rest is not.
- Study in people · done in people375%
- Review of studies · sums up other studies125%
Counted from the list of sources on this page. It counts only what we cite, so there may be more studies out there. A review counts once, however many studies it sums up.
Fig. 2 · evidence over time
The studies cover 4 different years, 2004 to 2018, counted from the list of sources on this page. The newest source on file is from 2018, more than five years ago. Research on it may have gone quiet.
Fig. 3 · legal status at a glance
US
Not approved
UK
Not approved
AU
Not approved
CA
Not approved
Not approved in any of the four countries shown. This is what the law says, not a verdict on the science. See Legal status below for the full text and any notes.
Fig. 4 · how much does what
Nobody has tested different amounts in people
This chart would show how the effect changes as the amount goes up. For this compound, nobody has measured that in people. So we leave it empty. We will not borrow an animal chart and pretend it works the same in people.
Fig. 5 · what the molecule is
- Kind of compound
- Blend
- Molecule weight
- Not on file
- Half-life
- Stated in words, not a numbersee the exact wording below
- Chain length
- None on file
Half-life as stated on file: Not defined for the blend, and the two halves do not match. No pharmacokinetic study of the mixture exists.
No amino acid sequence is on file for CJC-1295 with GHRP-2, which is expected: a blend is not built from amino acids.
Fig. 6 · what is in the vial
50%of a 10 mg CJC-1295 with GHRP-2 vial is CJC-1295 (no DAC)
- CJC-1295 (no DAC)5 mg50%
- GHRP-25 mg50%
What the label says is in a standard vial. It is not a dose, and not a lab test. The seller fixes the mix, so when you draw the amount you want of one ingredient, you get a set amount of every other one with it. No study has tested this mix in people or animals.
The studies we cite
- Study in people2006Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
A single shot of the long-acting version really does lift growth hormone for days. Healthy adults aged 21 to 61 took part in two small studies that stepped the dose up. Some got a dummy shot instead. Growth hormone ran two to ten times above its usual level for six days or more. The growth factor IGF-1 stayed up for nine to eleven days. One warning. This was the version with DAC, which makes it last. It is not the short-acting stuff usually sold as CJC-1295 without DAC.
Two randomised placebo-controlled ascending dose trials in healthy adults aged 21 to 61. A single subcutaneous injection produced dose-dependent rises in mean plasma growth hormone of two to ten-fold for six days or more and in IGF-1 of 1.5 to three-fold for nine to eleven days, with an estimated half-life of 5.8 to 8.1 days. This is the drug affinity complex version of CJC-1295, not the short-acting material usually sold as CJC-1295 without DAC.
- Study in people2004Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women
Putting the two drug types together does push growth hormone higher than either one alone. Healthy older adults got GHRH, GHRP-2, or both, through a drip over 24 hours. The pair beat each drug on its own. The extra boost from pairing them was three times bigger in young people than in older ones. It was bigger in older women than older men. A month of nonstop GHRP-2 kept growth hormone bursts raised. This was a drip in a research unit, not a seller's vial.
In healthy older adults, a 24 hour infusion of GHRP-2 combined with GHRH drove growth hormone secretion more than GHRH alone, and more than GHRP-2 alone. Acute two-peptide synergy was three-fold greater in young than older volunteers and 2.3-fold higher in elderly women than men. Thirty days of continuous GHRP-2 stimulated pulsatile growth hormone more than three-fold on day 1 and more than 1.8-fold at days 14 and 30, with IGF-1 on a stable plateau. This is the real combination evidence for the drug classes, using infusions in a research setting rather than a vendor vial.
- Study in people2005Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men
GHRP-2 makes healthy men hungrier. That is the drug itself at work, not a side story. It works on the same switch as the hunger hormone, and does the same job. That matters because the hunger comes with the product. Which GHRP a seller puts in the vial decides whether you spend the cycle fighting hunger. This was tested in healthy men, not in anyone trying to lose weight.
GHRP-2 increased food intake in healthy men in the way ghrelin does. The appetite effect is a direct pharmacological property of this half of the blend, and it is the reason the choice of GHRP changes the experience of the product.
- Review of studies2018The Safety and Efficacy of Growth Hormone Secretagogues
This is a review, not a test. It covers the two kinds of growth hormone boosters in this vial and what they do to growth hormone. It also covers the gap between what these drugs have been shown to do to hormone levels and what people claim they do for the body.
A review of the secretagogue class covering GHRH analogues and ghrelin-receptor agonists, their effects on the growth hormone axis, and the gap between their measured endocrine effects and the outcome claims made for them.
Where to buy CJC-1295 with GHRP-2
10 sellers list CJC-1295 with GHRP-2 in our latest read. They are ranked by trust score, then by archive rating, then by certificate tier, then by the lowest price per milligram. Archive evidence is counted before source-backed. Each path is out of 4, and the two are not added. A higher price does not raise the score. The letter is the certificate chip. 0 of them have a published certificate that names CJC-1295 with GHRP-2.
Some seller links may pay this site when you buy through them. A payment never changes a seller's tier or rank, and no seller has a say in any page.
| Seller | Trust score | Vial sizes | From, per mg | Certificate for CJC-1295 with GHRP-2 | Seller link |
|---|---|---|---|---|---|
| Peptide Shop A | 49 WeakSource-backed 2 of 4. Archive evidence 2 of 4.B | 10 mg | $8.40 | None found for CJC-1295 with GHRP-2 | View |
| USA Peptide Science Shop | 45 WeakSource-backed 2 of 4. Archive evidence 1 of 4.B | 10 mg | $9.00 | None found for CJC-1295 with GHRP-2 | View |
| Umbrella Labs | 39 WeakSource-backed 3 of 4. Archive evidence 2 of 4.A | 10 mg | $8.00 | None found for CJC-1295 with GHRP-2 | View |
| Peptide Pros | 39 WeakSource-backed 4 of 4. Archive evidence 1 of 4.B | 8 mg | $8.66 | None found for CJC-1295 with GHRP-2 | View |
| Peptides World | 39 WeakSource-backed 4 of 4. Archive evidence 1 of 4.B | 5 mg | $17.2 | None found for CJC-1295 with GHRP-2 | View |
| Limitless Biotech ST | 36 WeakSource-backed 1 of 4. Archive evidence 1 of 4.C | 10 mg | $8.40 | None found for CJC-1295 with GHRP-2 | View |
| Lejian Biotech Peptide | 35 WeakSource-backed 1 of 4. Archive evidence 1 of 4.C | 10 mg | $7.50 | None found for CJC-1295 with GHRP-2 | View |
| Peptides Sales | 28 InsufficientSource-backed 1 of 4. Archive evidence 1 of 4.C | 8 mg | $7.50 | None found for CJC-1295 with GHRP-2 | View |
| MJA Peptides | 25 InsufficientSource-backed 1 of 4. Archive evidence 1 of 4.C | 10 mg | $7.50 | None found for CJC-1295 with GHRP-2 | View |
| ZL Peptides | 25 InsufficientSource-backed 1 of 4. Archive evidence 1 of 4.C | 10 mg | $7.50 | None found for CJC-1295 with GHRP-2 | View |
- LC Lab-confirmed: the issuing laboratory echoed this certificate back
- A Current certificate, independent laboratory named, laboratory not yet checked
- B Certificate published, but no laboratory link, older than a year, or the laboratory did not recognise the published lookup
- C No certificate could be read
Every listing and vial size for CJC-1295 with GHRP-2 · How the trust score is counted
Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.
Common questions
Has CJC-1295 with GHRP-2 been tested in people?
Yes. 0 people given it across 2 completed trials cited here, 0 of which found nothing. CJC-1295 with GHRP-2 is a 10 mg vial split evenly between two kinds of growth hormone booster.
What is the CJC-1295 with GHRP-2 dosage?
No human dose established. Amounts that were given in studies sit in Human evidence on this page. None of them is a personal dose. 2 completed trials, 0 people given it
Is CJC-1295 with GHRP-2 FDA-approved?
Not approved. Neither part is an approved medicine in the United States, and the combination has never been reviewed.
Has this blend been tested?
The vial has not. The two drug kinds have. A 24 hour drip of GHRP-2 with GHRH raised growth hormone more than GHRH alone in healthy older adults. That study used a GHRH drip in a research unit, not a nightly shot from a 5 plus 5 vial.
Is the CJC-1295 in my vial the same as in the study?
Probably not. The study with six days of raised growth hormone, where half the drug was gone after 5.8 to 8.1 days, used CJC-1295 with DAC. Most no-DAC vials hold mod GRF 1-29, which works for minutes.
What does one unit deliver?
Take a 10 mg vial split evenly and mixed with 2 mL of water. Each unit mark holds 25 micrograms of each peptide. So a 4 unit draw is 100 micrograms of each.
GHRP-2 or ipamorelin?
GHRP-2 makes healthy men hungrier in a way you can measure. That is why people trying to lose fat usually switch to ipamorelin. Neither has a study showing a real-life result. So the honest way to choose is by side effects, not by what works.
Will my IGF-1 tell me it is working?
It will tell you your body responded. It will not tell you which half did it, because both end at the same place. And it will not tell you whether anything you care about changed, because no study of either peptide measured that.