CJC-1295 vs Tesamorelin
Written by Aaron CuhaReviewed Sep 2026
The short answer
An unapproved long acting copy of GHRH, against the one GHRH copy that is currently FDA approved. Both raise growth hormone and IGF-1. Only one of them has a measured result, less deep belly fat, tied to an approved use.
- CJC-1295 people
- 0
- CJC-1295 nulls
- 1
- Tesamorelin people
- 1,729
- Tesamorelin nulls
- 3
Dose
No human dose established
Amounts that circulate in forums and on vendor pages are not a human dose. Amounts that were given in studies sit in Human evidence on this page.
Commonly reported amounts for the no-DAC form, in mcg. The DAC form is usually reported in mg per week: enter that and switch the unit to mg.
Amounts commonly reported for the no-DAC form of CJC-1295, recorded for this archive's reconstitution calculator, are 100, 200 and 300 mcg. They are self-reports rather than trial doses, and this archive does not recommend any of them. No human dose has been established for CJC-1295.
| Reported amount | Where the number comes from |
|---|---|
| 100 mcg | Commonly reported, no published human dosing trial |
| 200 mcg | Commonly reported, no published human dosing trial |
| 300 mcg | Commonly reported, no published human dosing trial |
Dose
Approved medicine. No human dose established for unlabelled uses
Labeled amounts sit on the prescribing information. This page records what trials measured, not a personal dose.
FDA-approved (Egrifta) to cut extra belly fat in people with HIV who have lipodystrophy
First-hand reports are counted on each profile and never added together. This page sets two published records side by side. It does not pick a winner.
Column A
CJC-1295CJC-1295 (GHRH analogue)
A lab-made copy of the body's growth hormone releasing signal, built to last longer. It keeps growth hormone and IGF-1 raised for days.
Column B
TesamorelinTesamorelin (stabilized GHRH analogue)
An FDA-approved shot that shrinks belly fat, the deep fat around the organs. It is also being studied for memory and thinking in older adults at risk of Alzheimer's.
Side by side, on the facts we can check
| What we compare | CJC-1295 | Tesamorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| FDA status | Not FDA-approved | FDA-approved (Egrifta) to cut extra belly fat in people with HIV who have lipodystrophy |
| Half-life | ~6-8 days (DAC version) | ~26-38 minutes |
| Molecular weight | 3,647.2 Da | 5,135.9 Da |
| How it works | It switches on the GHRH receptor on the pituitary gland, which makes the gland release more growth hormone. The DAC version sticks to albumin in the blood, so it keeps working longer. | It switches on GHRH receptors on the pituitary gland. That makes the gland release growth hormone in natural bursts, and leaves the brain's normal checks on it in place. |
| Studies in people | 4 | 8 |
| Evidence | Limited: 2 completed trials, none stating how many people | Strong: 8 completed trials, 1,729 people given it |
| Legal status, US | Not approved; research use only | FDA-approved for one specific use, prescription only |
Frequently asked questions
What is the difference between CJC-1295 and Tesamorelin?
CJC-1295: A lab-made copy of the body's growth hormone releasing signal, built to last longer. It keeps growth hormone and IGF-1 raised for days. Tesamorelin: An FDA-approved shot that shrinks belly fat, the deep fat around the organs. It is also being studied for memory and thinking in older adults at risk of Alzheimer's.
Which has stronger research evidence, CJC-1295 or Tesamorelin?
Each compound gets a band worked out from facts we counted, with the math shown. CJC-1295 is Limited (2 completed trials, none stating how many people). Tesamorelin is Strong (8 completed trials, 1,729 people given it). That counts how much has been done in people. It does not rate whether either one works, and neither one is called the winner.
Are CJC-1295 and Tesamorelin FDA-approved?
CJC-1295: Not FDA-approved. Tesamorelin: FDA-approved (Egrifta) to cut extra belly fat in people with HIV who have lipodystrophy.
Related posts
Blog articles that cover CJC-1295 or Tesamorelin, newest first.
Reviewed Sep 2026. This page puts two published records side by side. It is for learning, and it is not medical advice. When this site shows a dose, it is the dose a trial or a clinic actually used, or what people say they did, with the source attached. None of it tells you what to take.