GB-115 dosage and evidence
Written by Aaron CuhaReviewed Sep 2026
The short answer
GB-115 is a Russian anti-anxiety pill made of two building blocks. It works on a gut and brain signal called CCK. Western sellers launched it in 2026 as a non-sedating alternative to benzodiazepines. All the published work is animal studies from one group, with no human trial.
Evidence grade for GB-115: Animal or lab only. The rule: only animal or lab studies on this page. No study in people yet. The sum on this page: 2 animal studies, no human study. A grade counts how much has been done to people, not whether it works.
- People given it
- 0
- Human studies
- 0
- Found nothing
- 0
Dose
No human dose established
No published study on this page has given this compound to people and reported a result.
2 animal studies, no human study
2 effects reported, 2 unwanted, by people using it, not a trial
In plain English
In plain English, from Aaron
This is how I would explain it to a friend. The evidence, with the numbers, is further down the page.
GB-115 is a Russian anti-anxiety pill made of two building blocks. It works on a gut and brain signal called CCK. Sellers call it a non-sleepy benzodiazepine alternative. It has never been tested in people.
What people take it for
- Calming anxiety without feeling sedated.
- Replacing benzodiazepines or phenibut.
What studies in people showed
There are no human studies. In rats and mice, it reduced anxious behavior without making them sleepy. All the work comes from one research group. Sellers in 2026 described a different target from the published science.
What people report
Reports, not study results
The good
- We have not collected user reports on this one yet.
The bad
- No human data of any kind, good or bad.
- Seller claims clash with the published science.
Where these come from: The findings come from the rodent studies on this page. We have no user reports.
My bottom line
Anxiety is worth treating properly. A rodent-only pill with confused marketing is not the way. Talk to a doctor.
An opinion, not a finding. I am a coach, not a doctor.
What it has been measured to do
Nothing indexed yet
The 2 citations on this page do not report a result for any of the 36 goals indexed here. Most of what sits here is something else: a listing of a planned study, a study of how the body handles the drug, a safety report or a government record. None of those tests whether it works.
Show full evidence
What is GB-115?
GB-115 is a Russian anti-anxiety pill made of two building blocks. It works on a gut and brain signal called CCK. Western sellers launched it in 2026 as a non-sedating alternative to benzodiazepines. All the published work is animal studies from one group, with no human trial.
GB-115 was made at the Zakusov Institute in Russia as a copy of CCK-4, a gut and brain signal. In rats and mice it calmed anxiety and acted like an antidepressant, without making them sleepy or showing signs of dependence. No human trial has been published. Seller descriptions in 2026 said it works on a different receptor, MC4. That clashes with the published science, so product claims are not reliable.
How does GB-115 work?
It acts on CCK receptors, which are part of the brain's anxiety wiring.
The evidence, in charts
Fig. 1a · how many people
0people have taken this in any study cited here
0 people · 0 studies in people
What this page cites instead is 2 animal studies. None of them gave the compound to a person.
Counted from the list of sources on this page. We draw this chart only when a study in people is cited. An empty one is the answer, not a gap in the page.
Fig. 1b · evidence mix
None of the 2 sources here are studies in people.
- Animal study · done in animals2100%
Counted from the list of sources on this page. It counts only what we cite, so there may be more studies out there. A review counts once, however many studies it sums up.
Fig. 2 · evidence over time
Sources here come from just two years, 2012 and 2013.
Too few different years on this page to draw a timeline. The newest source on file is from 2013, more than five years ago. Research on it may have gone quiet.
Fig. 3 · legal status at a glance
US
Not approved
UK
Not approved
AU
Not approved
CA
Not approved
Not approved in any of the four countries shown. This is what the law says, not a verdict on the science. See Legal status below for the full text and any notes.
Fig. 4 · how much does what
Nobody has tested different amounts in people
This chart would show how the effect changes as the amount goes up. For this compound, nobody has measured that in people. So we leave it empty. We will not borrow an animal chart and pretend it works the same in people.
Fig. 5 · what the molecule is
- Kind of compound
- Peptide
- Molecule weight
- 434.5 Da
- Half-life
- Stated in words, not a numbersee the exact wording below
- Chain length
- None on file
No amino acid sequence is on file for GB-115, so none is drawn rather than guessed from a name.
The studies we cite
- Animal study2013Anxiolytic activity of the dipeptide GB-115 in animal models
In rats and mice. It reduced anxious behavior.
Anxiolytic-like behavior in rodents.
- Animal study2012Role of the cholecystokinin system in anxiolytic activity of dipeptide GB-115
In rodents. Work from a single group on how it calms anxiety through the CCK system.
Single-group rodent data.
Where to buy GB-115
No seller we track lists GB-115 yet. We read sellers’ public product lists every week, and this section fills in as soon as one does. Every seller, graded
Common questions
Has GB-115 been tested in people?
Not in any study cited here. GB-115 is a Russian anti-anxiety pill made of two building blocks. It works on a gut and brain signal called CCK. Western sellers launched it in 2026 as a non-sedating alternative to benzodiazepines. All the published work is animal studies from one group, with no human trial.
What is the GB-115 dosage?
No human dose established. No published study on this page has given this compound to people and reported a result. 2 animal studies, no human study
Is GB-115 FDA-approved?
Not approved
Is GB-115 like phenibut?
It works a different way (CCK versus GABA-B). And unlike phenibut, it has no human data of any kind, good or bad.