PTD-DBM dosage and evidence
Written by Aaron CuhaReviewed Sep 2026
The short answer
PTD-DBM is a peptide you put on the scalp. It frees up a hair growth signal called Wnt. In mice it regrew hair and made new follicles. No human trial exists.
Evidence grade for PTD-DBM: Animal or lab only. The rule: only animal or lab studies on this page. No study in people yet. The sum on this page: 2 animal studies, no human study. A grade counts how much has been done to people, not whether it works.
- People given it
- 0
- Human studies
- 0
- Found nothing
- 0
Dose
No human dose established
No published study on this page has given this compound to people and reported a result.
2 animal studies, no human study
2 effects reported, 2 unwanted, by people using it, not a trial
In plain English
In plain English, from Aaron
This is how I would explain it to a friend. The evidence, with the numbers, is further down the page.
PTD-DBM is a peptide you put on the scalp. It frees up a hair growth signal that a blocking protein normally holds down. In mice it regrew hair and made new follicles. It has never been tested in people.
What people take it for
- Regrowing hair.
- An alternative or add-on to minoxidil.
What studies in people showed
No human study has been published. In a 2017 mouse study, it regrew hair and formed new follicles in wounded skin. Some mice also got valproic acid with it. Nobody has compared it with minoxidil in people.
What people report
Reports, not study results
The good
- We have not collected user reports on this one yet.
The bad
- No human safety data.
- Keeping this growth signal switched on for a long time is a possible cancer worry.
Where these come from: The findings come from the mouse studies on this page. We have no user reports.
My bottom line
One good mouse study is not a hair plan. If you are losing hair, start with a doctor and the treatments that have human data.
An opinion, not a finding. I am a coach, not a doctor.
What it has been measured to do
Nothing indexed yet
The 2 citations on this page do not report a result for any of the 36 goals indexed here. Most of what sits here is something else: a listing of a planned study, a study of how the body handles the drug, a safety report or a government record. None of those tests whether it works.
Show full evidence
What is PTD-DBM?
PTD-DBM is a peptide you put on the scalp. It frees up a hair growth signal called Wnt. In mice it regrew hair and made new follicles. No human trial exists.
PTD-DBM joins a piece that gets into cells with a piece that pulls a blocking protein, CXXC5, off the Wnt growth signal. That lets the signal run in hair follicle stem cells. In a 2017 study, PTD-DBM on the skin, alone and with valproic acid, regrew hair and made new follicles in wounded mouse skin. Korean cosmetic versions exist. No human study of benefit or safety has been published. Keeping the Wnt signal switched on for a long time is a possible cancer worry.
How does PTD-DBM work?
It pushes the blocking protein CXXC5 off its partner, which frees the Wnt growth signal in hair follicles.
The evidence, in charts
Fig. 1a · how many people
0people have taken this in any study cited here
0 people · 0 studies in people
What this page cites instead is 2 animal studies. None of them gave the compound to a person.
Counted from the list of sources on this page. We draw this chart only when a study in people is cited. An empty one is the answer, not a gap in the page.
Fig. 1b · evidence mix
None of the 2 sources here are studies in people.
- Animal study · done in animals2100%
Counted from the list of sources on this page. It counts only what we cite, so there may be more studies out there. A review counts once, however many studies it sums up.
Fig. 2 · evidence over time
Sources here come from just two years, 2015 and 2017.
Too few different years on this page to draw a timeline. The newest source on file is from 2017, more than five years ago. Research on it may have gone quiet.
Fig. 3 · legal status at a glance
US
Not approved
UK
Not approved
AU
Not approved
CA
Not approved
Not approved in any of the four countries shown. This is what the law says, not a verdict on the science. See Legal status below for the full text and any notes.
Fig. 4 · how much does what
Nobody has tested different amounts in people
This chart would show how the effect changes as the amount goes up. For this compound, nobody has measured that in people. So we leave it empty. We will not borrow an animal chart and pretend it works the same in people.
Fig. 5 · what the molecule is
- Kind of compound
- Peptide
- Molecule weight
- 3,082.6 Da
- Half-life
- Stated in words, not a numbersee the exact wording below
- Chain length
- None on file
No amino acid sequence is on file for PTD-DBM, so none is drawn rather than guessed from a name.
The studies we cite
- Animal study2017Targeting of CXXC5 by a competing peptide stimulates hair regrowth and wound-induced hair neogenesis
In mice. Put on the skin, it helped hair regrow and new follicles form in wounds.
Topical PTD-DBM promoted hair regrowth and wound-induced follicle neogenesis in mice.
- Animal study2015The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing
In mice. It shows CXXC5 slows wound healing. That is the protein PTD-DBM pushes aside.
Establishes CXXC5 as the target that PTD-DBM displaces.
Where to buy PTD-DBM
11 sellers list PTD-DBM in our latest read. They are ranked by trust score, then by archive rating, then by certificate tier, then by the lowest price per milligram. Archive evidence is counted before source-backed. Each path is out of 4, and the two are not added. A higher price does not raise the score. The letter is the certificate chip. 1 of them has a published certificate that names PTD-DBM.
Some seller links may pay this site when you buy through them. A payment never changes a seller's tier or rank, and no seller has a say in any page.
| Seller | Trust score | Vial sizes | From, per mg | Certificate for PTD-DBM | Seller link |
|---|---|---|---|---|---|
| Core Peptides | 75 StrongSource-backed 4 of 4. Archive evidence 2 of 4.A | 5 mg | $17.8 | None found for PTD-DBM | View |
| Biotech Peptides | 49 WeakSource-backed 3 of 4. Archive evidence 3 of 4.A | 5 mg | $17.2 | Certificate, MZ Biolabs | View |
| Core Peptides Official | 49 WeakSource-backed 3 of 4. Archive evidence 2 of 4.A | 5 mg | $16.0 | None found for PTD-DBM | View |
| Luxe Peptides | 49 WeakSource-backed 3 of 4. Archive evidence 2 of 4.A | 5 mg | $16.0 | None found for PTD-DBM | View |
| Peptide Shop A | 49 WeakSource-backed 2 of 4. Archive evidence 2 of 4.B | 5 mg | $17.2 | None found for PTD-DBM | View |
| Peptides World | 39 WeakSource-backed 4 of 4. Archive evidence 1 of 4.B | 5 mg | $17.8 | None found for PTD-DBM | View |
| Limitless Biotech ST | 36 WeakSource-backed 1 of 4. Archive evidence 1 of 4.C | 5 mg | $17.8 | None found for PTD-DBM | View |
| Lejian Biotech Peptide | 35 WeakSource-backed 1 of 4. Archive evidence 1 of 4.C | 5 mg | $16.0 | None found for PTD-DBM | View |
| Huaian Hanyou Peptide | 25 InsufficientSource-backed 1 of 4. Archive evidence 1 of 4.C | 5 mg | $16.0 | None found for PTD-DBM | View |
| MJA Peptides | 25 InsufficientSource-backed 1 of 4. Archive evidence 1 of 4.C | 5 mg | $16.0 | None found for PTD-DBM | View |
| ZL Peptides | 25 InsufficientSource-backed 1 of 4. Archive evidence 1 of 4.C | 5 mg | $16.0 | None found for PTD-DBM | View |
- LC Lab-confirmed: the issuing laboratory echoed this certificate back
- A Current certificate, independent laboratory named, laboratory not yet checked
- B Certificate published, but no laboratory link, older than a year, or the laboratory did not recognise the published lookup
- C No certificate could be read
Every listing and vial size for PTD-DBM · How the trust score is counted
Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.
Common questions
Has PTD-DBM been tested in people?
Not in any study cited here. PTD-DBM is a peptide you put on the scalp. It frees up a hair growth signal called Wnt. In mice it regrew hair and made new follicles. No human trial exists.
What is the PTD-DBM dosage?
No human dose established. No published study on this page has given this compound to people and reported a result. 2 animal studies, no human study
Is PTD-DBM FDA-approved?
Not approved; nobody has asked the FDA to test it in people (no IND)
Does PTD-DBM beat minoxidil?
No trial has compared them in people. The evidence is one mouse study of regrowth and new follicles.
Latest reading on PTD-DBM
Blog posts about PTD-DBM, newest first.