Is Klotho legal in the United Kingdom?

Nobody has given klotho to a person in a published study. People with higher blood levels tend to live longer and think better. A gene therapy is heading toward studies in people. Products sold online as klotho peptide are not the protein that was studied.

First, a mix-up almost every article makes. Alpha-klotho and beta-klotho are different genes that make different proteins.

How it works: Loose klotho in the blood works with the hormone FGF23. It also tunes the insulin and IGF-1 signals, the Wnt signal, and the body's defence against oxidation.

Approval history: No approved product; a gene therapy that has not yet asked the FDA to start human studies (pre-IND)

Licenses medicines for sale in the UK. A compound without a licence to be sold (a marketing authorisation) is an unlicensed medicine. The law only lets it reach people through a prescriber, under the specials scheme (unlicensed medicines made for one patient's needs). It cannot be sold as a research product.

The legal category above is how The Longevity Archive reads Medicines and Healthcare products Regulatory Agency listings for Klotho on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check MHRA directly

Whether Klotho is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in the United Kingdom. Before you compete or get tested, look up Klotho by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.