Legal status · Canada
Is MET-233i legal in Canada?
Written by Aaron CuhaReviewed Sep 2026
Direct answer
No. MET-233i is not approved for any medical use in Canada. Its legal category is "Investigational, not approved". The only legal way to get it is to join a registered clinical trial (an official study in people). A "research use only" label on vials sold online does not make them legal to use in people. On the evidence, 1 completed human trial is cited on its profile.
- People given it
- 0
- Found nothing
- 0
Legal category
Investigational, not approved
Health Canada authorisation and DIN status, from the MET-233i profile.
Reviewed Sep 2026. This is a legal category, not legal advice.
A "research use only" label on a vial does not make it legal to use on people.
MET-233i in Canada at a glance
| Legal category | Investigational, not approved |
|---|---|
| Health Canada approval status | Not approved by Health Canada; investigational (still being tested in trials) |
| Studies in people | 1 of 2 sources on the profile |
| Reviewed | Sep 2026 |
The legal category and note come from the MET-233i profile. We checked them against Health Canada, Health Products and Food Branch (Health Canada) listings on the reviewed date.
What this means
- 01
MET-233i is being tested in registered clinical trials (official studies in people). Health Canada has not approved it for sale in Canada.
- 02
The only legal ways for a person to get it are to join a trial, or to use an official early-access program where one exists. There is no pharmacy product to prescribe.
- 03
Vials sold online "for research use only" are not trial supplies. That label does not make them legal to use in people.
What MET-233i is
Pfizer's monthly amylin shot, from Metsera. It stays in the body about 19 days. It is being mixed with berobenatide into one monthly GLP-1 and amylin shot.
MET-233i is an experimental amylin drug. Amylin is a hormone that makes you feel full.
How it works: It turns on amylin receptors for a very long time. It is built for monthly shots, alone or with a GLP-1 drug.
Approval history: Investigational; in mid-stage studies (as a combination)
How Health Canada treats this kind of product
Allows a drug to be sold by issuing a Notice of Compliance and a Drug Identification Number (DIN). A compound that is not allowed for sale cannot legally be sold for use in people. Bringing in prescription drugs for your own use is also limited.
The legal category above is how The Longevity Archive reads Health Canada, Health Products and Food Branch listings for MET-233i on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.
MET-233i in sport and the military
Whether MET-233i is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in Canada. Before you compete or get tested, look up MET-233i by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.
- WADA Prohibited List
- Global DRO (check a named product)
- USADA (US athletes)
- Operation Supplement Safety (US service members)
The rules you compete or serve under decide this, not this page.
MET-233i in other countries
Frequently asked questions
Is MET-233i legal in Canada?
No. MET-233i is not approved for any medical use in Canada. Its legal category is "Investigational, not approved". The only legal way to get it is to join a registered clinical trial (an official study in people). A "research use only" label on vials sold online does not make them legal to use in people. On the evidence, 1 completed human trial is cited on its profile.
Can I buy MET-233i in Canada?
There is no approved product to buy. In Canada, MET-233i has the legal category "Investigational, not approved". So no licensed pharmacy product exists. Sellers who list it "for research use only" are not selling it for use in people, and that label does not change its legal status. Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.
Is MET-233i Health Canada approved?
No. In Canada, MET-233i has the legal category "Investigational, not approved". That is not a Health Canada approval to sell it. For comparison, its US FDA status is: Investigational; in mid-stage studies (as a combination). On the evidence, 1 completed human trial is cited on its profile.
Related compounds in Canada
Full research profile
How MET-233i works, the studies we cite, FDA status and the full legal summary are all on its compound profile.
MET-233i profileThis page is general information about the legal status of MET-233i in Canada, current as of Sep 2026. It is not legal advice. Legal status changes. For your own situation, check with Health Canada, Health Products and Food Branch or ask a lawyer. Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use. Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.