Is TB-500 legal in Australia?

A lab-made chain of seven amino acids cut from thymosin beta-4, sold under a research name. No published study has given TB-500 to people. The human studies people quote for it used the full 43 amino acid parent peptide, which is a different molecule.

TB-500 is not the same thing as thymosin beta-4, even though sellers use the two names as if they were. The FDA's July 2026 review defines TB-500 as a lab-made chain of seven amino acids, written Ac-LKKTETQ.

How it works: The fragment holds LKKTET, the part of thymosin beta-4 that grabs actin. Actin is a protein that lets cells move and change shape.

Approval history: Not FDA-approved. In April 2026 the FDA took it off Category 2, its list of pharmacy ingredients with safety worries. In July 2026 the FDA's Pharmacy Compounding Advisory Committee voted 8 to 6, with one member abstaining, in favor of letting pharmacies make it. The FDA's own reviewers had advised against that. The FDA has not acted yet

Registers or lists medicines and health products on the ARTG, its official register. It also sorts substances into schedules in the Poisons Standard. Many peptides are Schedule 4 (prescription only). So having them without a prescription, or importing them for yourself, is restricted. That is true even when no product is registered.

The legal category above is how The Longevity Archive reads Therapeutic Goods Administration listings for TB-500 on the reviewed date. It is not a legal opinion. Rules change. Bringing a compound into the country, prescribing it and owning it can each be treated differently. Check with the agency before you act on anything here.

Check TGA directly

Whether TB-500 is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status in Australia. Before you compete or get tested, look up TB-500 by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.

• WADA Prohibited List
• Global DRO (check a named product)
• USADA (US athletes)
• Operation Supplement Safety (US service members)

The rules you compete or serve under decide this, not this page.