Is Trigonelline legal?
Written by Aaron CuhaReviewed Sep 2026
- US: Sold as a dietary supplement
- UK: Sold as a supplement
- AU: Available as a supplement
- CA: Sold as a supplement
The US comes first because most people ask about it. Each country has its own page. It names the agency, the law or rule, and what the legal category means in real life.
All four countries, side by side
| What we list | United States · FDA | United Kingdom · MHRA | Australia · TGA | Canada · Health Canada |
|---|---|---|---|---|
| Status | Not approved | Not approved | Not approved | Not approved |
| Legal category | Sold as a dietary supplement | Sold as a supplement | Available as a supplement | Sold as a supplement |
| Note | None recorded | None recorded | None recorded | None recorded |
| Agency | Check FDA directly | Check MHRA directly | Check TGA directly | Check Health Canada directly |
US FDA status: Dietary supplement; not a drug. Reviewed Sep 2026.
Country by country
Is Trigonelline legal in the United States?
Trigonelline can be sold in the United States as a supplement or cosmetic ingredient. Its legal category is "Sold as a dietary supplement". That is not approval as a drug. FDA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, no study in people is cited on its profile.
The full United States answerIs Trigonelline legal in the United Kingdom?
Trigonelline can be sold in the United Kingdom as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. MHRA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, no study in people is cited on its profile.
The full United Kingdom answerIs Trigonelline legal in Australia?
Trigonelline can be sold in Australia as a supplement or cosmetic ingredient. Its legal category is "Available as a supplement". That is not approval as a drug. TGA has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, no study in people is cited on its profile.
The full Australia answerIs Trigonelline legal in Canada?
Trigonelline can be sold in Canada as a supplement or cosmetic ingredient. Its legal category is "Sold as a supplement". That is not approval as a drug. Health Canada has not checked any health claim made for it. Versions you inject, and "research use only" versions, fall outside supplement rules, so that label does not make them legal to use in people. On the evidence, no study in people is cited on its profile.
The full Canada answerTrigonelline in sport and the military
Whether Trigonelline is banned in sport is set by the World Anti-Doping Code and by military rules, not by its legal status. Before you compete or get tested, look up Trigonelline by name on the Prohibited List, or look up a named product in Global DRO. Under the World Anti-Doping Code, category S0 bans, at all times, any drug-like substance that meets two tests. No other section of the List covers it. And no government health regulator anywhere has a current approval for it as a treatment in people. Many substances that are approved somewhere are banned by name in another section. So approval does not mean a substance is allowed in sport.
- WADA Prohibited List
- Global DRO (check a named product)
- USADA (US athletes)
- Operation Supplement Safety (US service members)
The rules you compete or serve under decide this, not this page.
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General information, current as of Sep 2026. Not legal advice. Legal status changes. For your own situation, check with the agency or a lawyer. Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use. Sellers named on the price pages are ranked by certificate tier, then price, and any affiliate income is disclosed there. Naming a seller is not a recommendation to buy or use anything.