Legal status · Canada
Is Trodusquemine legal in Canada?
No. Trodusquemine is not an approved medicine in Canada; its classification is "Not authorized for sale". Nothing containing it is authorized for any use in people. Vials labeled "for research use only" are not exempt: that label does not make human use lawful. Human evidence: Preliminary.
Trodusquemine in Canada at a glance
| Classification | Not authorized for sale |
|---|---|
| Health Canada approval status | Not approved by Health Canada |
| Evidence level | Preliminary (research strength: Preliminary) |
| Reviewed | Sep 2026 |
Classification and note come from the Trodusquemine profile, checked against Health Canada, Health Products and Food Branch (Health Canada) listings at the reviewed date.
What this means
- 01
No product containing Trodusquemine is approved by Health Canada for any use in Canada, so nothing on the market is authorized for people.
- 02
"Research use only" is a vendor label, not a legal category that permits human use. It does not exempt a product from medicines law.
- 03
Importing, supplying or promoting it for human use can fall under medicines legislation in Canada. This page is general information, not legal advice.
What Trodusquemine is
An aminosterol PTP1B inhibitor from dogfish shark that regenerated heart tissue in zebrafish and mice and caused fat-specific weight loss in obese mice; early human trials never produced published efficacy.
Trodusquemine blocks protein tyrosine phosphatase 1B, a brake on insulin and leptin signaling, and crosses into the brain. Animal studies showed weight loss confined to fat and regeneration of heart and other tissues after injury.
Mechanism: Allosteric, non-competitive PTP1B inhibition enhancing insulin and leptin signaling; regenerative effects via PTP1B-dependent pathways in injured tissue.
Regulatory history: Investigational history; not approved
How Health Canada treats this kind of product
Authorises drugs for sale through a Notice of Compliance and Drug Identification Number. A compound that is not authorised for sale cannot lawfully be sold for human use, and personal importation of prescription drugs is limited.
The classification above is the The Longevity Archive reading of Health Canada, Health Products and Food Branch listings for Trodusquemine at the reviewed date, not a legal opinion. Rules change, and importing, prescribing and possessing a compound can each be treated differently. Check the regulator directly before acting on anything here.
Trodusquemine in other countries
United States
Not approvedNot approved; sold 'for research use only'
Is Trodusquemine legal in the United States?United Kingdom
Not approvedUnlicensed medicine; supply for human use is unlawful
Is Trodusquemine legal in the United Kingdom?Australia
Not approvedNot approved; Schedule 4 or import-restricted
Is Trodusquemine legal in Australia?Frequently asked questions
Is Trodusquemine legal in Canada?
No. Trodusquemine is not an approved medicine in Canada; its classification is "Not authorized for sale". Nothing containing it is authorized for any use in people. Vials labeled "for research use only" are not exempt: that label does not make human use lawful. Human evidence: Preliminary.
Can I buy Trodusquemine in Canada?
No approved product exists to buy. In Canada Trodusquemine is classified as "Not authorized for sale", so there is no licensed pharmacy product. Vendors selling it "for research use only" are not selling it for human use, and that label does not change its legal status. This site does not list or recommend vendors.
Is Trodusquemine Health Canada approved?
No. In Canada Trodusquemine is classified as "Not authorized for sale", which is not a Health Canada marketing approval. For comparison, the US FDA status is: Investigational history; not approved. Evidence level: Preliminary.
Related compounds in Canada
Full research profile
Mechanism, cited studies, FDA status and the full legal summary for Trodusquemine live on its compound profile.
Trodusquemine profileThis page is general information about the regulatory status of Trodusquemine in Canada, current as of Sep 2026. It is not legal advice, and classifications change; check Health Canada, Health Products and Food Branch directly or consult a lawyer for a specific situation. Educational use only. This database summarizes published research. It is not medical advice and contains no dosing protocols or recommendations for personal use. The Longevity Archive has no vendor relationships and does not recommend where to buy anything.