Peptide finder

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Pick as many as you like. The number on each one is how many people it has been measured in across the whole archive. So you can see where the evidence is before you choose.

1. 01NattokinaseBiologicStrong. At least two finished studies in people, and at least 1,000 people who took it. 9 completed trials, 1,795 people given it.6 reported

   608 people4 studies1 found nothing

   • found nothingThe one long, careful, independent trial found nothing. 265 adults without heart disease took nattokinase or a dummy pill for a median of three years, with neck artery scans every six months. The artery wall thickened at the same rate in both groups. Stiffness, blood pressure, and every clotting, inflammation and...

     Clinical Hemorheology and Microcirculation, 2021 · 265 people

   • In a better built trial, nattokinase alone moved one blood fat and nothing else. 178 patients with stable heart disease, already on their usual medicines, took nattokinase, red yeast rice, both, or a dummy pill for 90 days. Nattokinase alone lowered LDL, the harmful cholesterol, compared with the dummy. Total...

     Frontiers in Nutrition, 2024 · 178 people

   • Nattokinase lowered blood pressure a little. 86 adults with borderline or mild high blood pressure took it or a dummy pill for eight weeks. The top number came down about 5 points more than on the dummy, and the bottom number by nearly 3. A hormone that helps set blood pressure fell at the same time, which fits. A few...

     Hypertension Research, 2008 · 86 people

2. 02PT-141PeptideStrong. At least two finished studies in people, and at least 1,000 people who took it. 4 completed trials, 2,355 people given it.9 reported

   397 people1 study

   • Bremelanotide raises blood pressure a little and slows the heart, for a short while after each shot. 397 premenopausal women wore blood pressure monitors around the clock. At the label dose the top blood pressure number ran about 3 mmHg higher than on the dummy in the four hours after the shot, with peaks usually...

     Journal of Hypertension, 2017 · 397 people

3. 03ResveratrolSupplementModerate. At least one finished study in people, and at least 100 people who took it. 14 completed trials, 403 people given it.7 reported

   213 people5 studies3 found nothing

   • found nothingThe longest and largest diabetes trial of resveratrol found nothing that counted. 192 patients took 40 mg, 500 mg or a dummy pill every day for six months. An inflammation marker fell further on resveratrol, but not by enough to call real. Weight, waist, blood pressure, blood sugar, insulin and a string of other...

     Pharmacological Research, 2016 · 192 people

   • This is the strongest good human result resveratrol has, and it rests on eleven men. Obese but otherwise healthy men took 150 mg a day for a month, and also spent a month on a dummy pill. Their resting metabolism slowed the way it does when people eat less. Liver fat, blood sugar, triglycerides, a liver enzyme and...

     Cell Metabolism, 2011 · 11 people

   • found nothingTen older adults took resveratrol for a month and their blood sugar after meals came down. The peak reading fell by about a tenth, the total sugar load over three hours fell, and their response to insulin improved. Fasting sugar, weight, blood pressure and cholesterol did not move. There was no comparison group, and...

     Journals of Gerontology Series A, 2012 · 10 people

4. 04ANPPeptideModerate. At least one finished study in people, and at least 100 people who took it. 4 completed trials, 188 people given it.4 reported

   184 people2 studies

   • Head to head against a water tablet called tolvaptan, this drug came off slightly worse. 109 people in hospital with heart failure got either tolvaptan or carperitide. Symptoms and a blood test for heart strain improved about equally on both. Blood pressure ran lower on carperitide. More people on carperitide had to...

     Journal of Clinical Pharmacology, 2013 · 109 people

   • This looked for who passes more water on the drug, and found two blood tests that predict it. 75 people in hospital with heart failure got a low dose of carperitide through a drip for six hours. Those who started with lower levels of their own natriuretic hormone, and lower vasopressin, produced the most urine. Blood...

     ESC Heart Failure, 2022 · 75 people

5. 05TaurineSupplementModerate. At least one finished study in people, and at least 100 people who took it. 1 completed trial, 120 people given it.5 reported

   120 people1 study

   • Taurine can move blood pressure in people who are already on the high side of normal. 120 adults took 1.6 grams a day, or a dummy pill, for 12 weeks. The top number of their blood pressure, measured in the clinic, fell 7.2 points on taurine against 2.6 on the dummy. This is a blood pressure study, not an ageing study.

     Hypertension, 2016 · 120 people

6. 06PterostilbeneSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 80 people given it.4 reported

   80 people1 study

   • It pushed blood pressure down and bad cholesterol up. 80 adults with raised cholesterol took pterostilbene at 125 mg twice a day, at 50 mg twice a day, at 50 mg with grape extract, or a dummy, for 6 to 8 weeks. On pterostilbene alone, bad cholesterol rose 17.1 units. Adding grape extract removed that rise. On the high...

     Evidence-Based Complementary and Alternative Medicine, 2014 · 80 people

7. 07ElamipretidePeptideModerate. At least one finished study in people, and at least 100 people who took it. 5 completed trials, 487 people given it.6 reported

   71 people1 study1 found nothing

   • found nothingElamipretide was tested in failing hearts and it changed nothing. Seventy one people with a weak heart pump got a dummy injection or one of two elamipretide doses, daily for four weeks. Ultrasound scans of how much blood the heart held and how much it pushed out looked the same in all three groups. The trial was small...

     Journal of Cardiac Failure, 2020 · 71 people

8. 08MifepristoneSmall moleculeModerate. At least one finished study in people, and at least 100 people who took it. 2 completed trials, 320 people given it.4 reported

   50 people1 study

   • In Cushing's syndrome, where cortisol is the problem, blocking its receptor with mifepristone improved blood sugar, blood pressure and weight over six months. 50 adults took part, and there was no dummy pill group. Tiredness, nausea, headache and low potassium were common. This is the approved use, not a study of...

     The Journal of Clinical Endocrinology and Metabolism, 2012 · 50 people

9. 09EpicatechinSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 4 completed trials, 44 people given it.1 reported

   37 people2 studies2 found nothing

   • found nothingPure epicatechin did not improve blood vessel function, and the small insulin change is easy to over-read. 37 adults aged 40 to 80 with raised blood pressure took 100 mg a day for four weeks, and each also took a dummy for four weeks, in turn. Artery widening improved slightly, too little to separate from chance....

     American Journal of Clinical Nutrition, 2015 · 37 people

   • found nothingA food-sized dose of pure epicatechin did nothing. 48 overweight or obese non-smokers with features of metabolic syndrome took 25 mg a day for two weeks, and each took a dummy for two weeks as well, in turn. Nothing moved: not blood pressure, glucose, insulin, triglycerides, or any cholesterol measure. The authors...

     American Journal of Clinical Nutrition, 2018 · number of people not given

10. 10DanazolHormoneLimited. People have taken it in a published study, but fewer than 100 of them. 3 completed trials, 63 people given it.5 reported

    36 people1 study

    • This is what danazol costs, measured in a different illness. 36 patients with acquired aplastic anaemia took danazol on its own, 10 mg per kilogram a day up to a cap of 600 mg. After six months, good cholesterol had fallen 30 percent and bad cholesterol had risen 11 percent. The size of the heart's main pumping...

      Blood Cells, Molecules and Diseases, 2025 · 36 people

11. 11ForskolinSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 53 people given it.5 reported

    23 people1 study1 found nothing

    • found nothingThe same supplement was tested in women and it did not work. 23 mildly overweight women took a 10 percent Coleus forskohlii extract twice a day or a dummy for 12 weeks, seven on the extract. Fat mass, lean mass and body fat percentage came out the same in both groups. Slight leanings toward less weight gain were too...

      Journal of the International Society of Sports Nutrition, 2005 · 23 people

12. 12GalaninPeptideLimited. People have taken it in a published study, but fewer than 100 of them. 4 completed trials, 21 people given it.

    8 people2 studies1 found nothing

    • Galanin has a real effect on the body's automatic controls, and this is the study that shows it. Eight healthy young men were infused for an hour, or given salt water instead. On galanin, the stress chemical noradrenaline fell by more than half while they lay down, and barely rose when they stood up. Their resting...

      The Journal of Clinical Endocrinology and Metabolism, 1995 · 8 people

    • found nothingThe first time galanin was given to people, it set off a surge of growth hormone. Ten healthy volunteers were infused for an hour at one of two rates. Growth hormone climbed many times over, further at the higher rate. The hormone behind milk production rose a little. Stress and thyroid hormones did not move, and...

      The Lancet, 1986 · number of people not given

13. 13NMNSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 4 completed trials, 94 people given it.6 reported

    number of people not given1 study1 found nothing

    • found nothingA high dose NMN tablet raised NAD in the blood and moved weight and cholesterol, but not muscle. 30 overweight or obese adults took MIB-626, 1000 mg twice a day, or a dummy pill, for 28 days. Weight fell 1.9 kg. The lower blood pressure number and LDL cholesterol fell too. Strength, tiredness, fitness and stair...

      Journal of Clinical Endocrinology and Metabolism, 2023 · number of people not given

14. 14VIPPeptideLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.2 reported

    number of people not given1 study

    • A small, early study in a serious lung condition, with everyone knowing what they were getting. People with high blood pressure in the lungs breathed in VIP. Pressures in the lung circuit improved and they could walk further. All of them were short of VIP to begin with, which is the best case there is for giving it...

      Journal of Clinical Investigation, 2003 · number of people not given

15. 15MIB-626SupplementModerate. At least one finished study in people, and at least 100 people who took it. 4 completed trials, 107 people given it.1 reported

    number of people not given1 study1 found nothing

    • found nothingThe tablet moved some body measurements and left every measure of physical function untouched. 30 overweight or obese adults aged 45 and over took MIB-626 or a dummy tablet for four weeks. Weight fell by about two kilograms. Blood pressure and cholesterol both came down. Strength, stamina, how quickly muscles tired...

      Journal of Clinical Endocrinology and Metabolism, 2023 · number of people not given

16. 16Thymalin with epitalonBlendStrong. At least two finished studies in people, and at least 1,000 people who took it. 2 completed trials, 1,106 people given it.7 reported

    number of people not given1 study

    • This is the study the thymalin story rests on, and it is not built to carry that weight. 266 older people were followed for six to eight years, and given thymalin and epithalamin in the first two or three. Infections and deaths were reported at about half the rate of a comparison group, and several age-related...

      Neuro Endocrinology Letters, 2003 · number of people not given

17. 17ErythropoietinBiologicStrong. At least two finished studies in people, and at least 1,000 people who took it. 3 completed trials, 4,641 people given it.6 reported

    number of people not given1 study

    • The stroke harm was real and there is no way to screen for it. Researchers went through all 154 strokes in the earlier trial. Five in every hundred on darbepoetin had a stroke, against about two and a half on the dummy injection. Being assigned the drug predicted stroke on its own. It could not be explained away by...

      Circulation, 2011 · number of people not given

18. 18ClenbuterolSmall moleculeLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 11 people given it.5 reported

    7 people1 study1 found nothing

    • found nothingClenbuterol built leg muscle in heart failure patients and did nothing for their hearts. 7 people supported by a mechanical heart pump took rising oral doses for three months, up to a very high daily amount. Body weight and lean mass rose, and thigh strength improved from about 37 to about 46 kilograms of force. The...

      The Journal of Heart and Lung Transplantation, 2006 · 7 people

19. 19FOXO4-DRIPeptideLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 74 people given it.8 reported

    number of people not given0 studies

    • In mice and rats, this is the result that cuts the other way, and it is usually left out. In mice, clearing worn-out cells from lung blood vessels, with FOXO4-DRI among the tools, raised pressure in the lung circulation. It thickened the right side of the heart and stripped out lining cells the lung depends on. In...

      Circulation, 2023 · number of people not given

20. 20NavitoclaxSmall moleculeModerate. At least one finished study in people, and at least 100 people who took it. 2 completed trials, 137 people given it.2 reported

    number of people not given0 studies

    • In mice. Clearing worn-out cells, including with navitoclax, made high blood pressure in the lungs worse in several mouse models. That is a harm signal. It is listed here because the good results in animals get quoted all the time and this one does not.

      Circulation, 2023 · number of people not given

21. 21TesofensineSmall moleculeLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.8 reported

    number of people not given0 studies
22. 22HGH Fragment 176-191PeptideAnimal or lab only. Only animal or lab studies on this page. No study in people yet. 4 animal studies, no human study.5 reported

    number of people not given0 studies
23. 23HCGBiologicLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 55 people given it.8 reported

    number of people not given0 studies
24. 24Nicotinamide RibosideSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 4 completed trials, 90 people given it.5 reported

    number of people not given0 studies