Peptide finder

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Pick as many as you like. The number on each one is how many people it has been measured in across the whole archive. So you can see where the evidence is before you choose.

1. 01LandogrozumabBiologicModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 726 people given it.

   601 people2 studies1 found nothing

   • The same antibody was tested around hip replacement surgery, and again it built muscle. Four hundred adults having a planned hip replacement were split by chance between three doses and a dummy injection. Twelve weeks later, arm and leg muscle had risen at every dose, and it rose more the higher the dose. The dummy...

     ClinicalTrials.gov, 2014 · 400 people

   • found nothingA myostatin antibody added muscle to older people who fall, and barely moved how they function. Two hundred older adults were split by chance between the drug and a dummy injection. After six months the drug group had gained about four hundred grams of arm and leg muscle, while the dummy group had lost a little....

     Lancet Diabetes and Endocrinology, 2015 · 201 people

2. 02EcdysteroneSupplementModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 233 people given it.5 reported

   233 people2 studies1 found nothing

   • found nothingThe drug version of this molecule was tested in 233 older adults losing muscle with age. It missed its main target. Across everyone who took part, walking speed over a 400 metre course barely changed compared with a dummy pill. A smaller group who stuck to the plan walked a little faster. Counting only those people is...

     Journal of Cachexia, Sarcopenia and Muscle, 2025 · 233 people

   • In a study in people, those taking ecdysterone gained more muscle than the comparison group and lifted more on the bench press. Blood tests for liver and kidney damage did not rise. The researchers checked everyone for banned drugs and tested the supplement for hidden steroids first. They said it should go on the...

     Archives of Toxicology, 2019 · number of people not given

3. 03BIO101Small moleculeModerate. At least one finished study in people, and at least 100 people who took it. 1 completed trial, 233 people given it.3 reported

   233 people2 studies1 found nothing

   • found nothingIt missed the target it was built to hit. 233 older adults losing muscle with age, average age 75, took BIO101 at one of two doses or a dummy pill for six months. The measure was walking speed over 400 metres. Counting everyone, the drug made almost no difference. Covid wiped out more than half the final in-person...

     Journal of Cachexia, Sarcopenia and Muscle, 2025 · 233 people

   • The same molecule worked in young people who train and fell short in frail older people. In a sports study, ecdysterone added muscle and bench press strength. In older adults losing muscle with age, the drug version did not clearly improve walking speed. A gain in the gym in young healthy bodies does not mean an older...

     Archives of Toxicology, 2019 · number of people not given

4. 04RetatrutidePeptideStrong. At least two finished studies in people, and at least 1,000 people who took it. 5 completed trials, 1,345 people given it.8 reported

   189 people1 study

   • Most of the weight lost was fat, on scans from a small slice of a larger trial. 189 people joined the scan study and only 103 had usable scans at both the start and week 36. Fat mass fell 26.1% and 23.2% at the two higher doses, against 4.5% on the dummy shot. The share of the loss that was muscle looked like what...

     The Lancet Diabetes & Endocrinology, 2025 · 189 people

5. 05EnobosarmSmall moleculeModerate. At least one finished study in people, and at least 100 people who took it. 1 completed trial, 159 people given it.5 reported

   159 people1 study1 found nothing

   • found nothingMuscle did grow, in people who were losing it to cancer. 159 patients who had already lost weight took one of two doses of enobosarm or a dummy pill for up to about four months. Muscle mass rose on both doses, by roughly 1 to 1.5 kg, while the dummy group did not change. Here is the limit. Growing muscle is not the...

     The Lancet Oncology, 2013 · 159 people

6. 06MetforminSmall moleculeModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 489 people given it.6 reported

   94 people1 study

   • Metformin got in the way of the muscle that lifting weights is meant to build. 94 adults aged 65 and over trained with weights for 14 weeks under supervision. Half took metformin every day, half took a dummy pill. The dummy group put on more lean weight and more thigh muscle, and their thigh muscle came out denser....

     Aging Cell, 2019 · 94 people

7. 07TeduglutidePeptideLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 83 people given it.4 reported

   83 people1 study

   • It worked, and the doses came out backwards. People with short bowel syndrome cannot absorb enough from food, so they are fed through a vein, often for hours every night. 83 of them got one of two doses of teduglutide or a dummy injection for about six months. The lower dose beat the dummy. The higher dose did not,...

     Gut, 2011 · 83 people

8. 08MecaserminPeptideLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 76 people given it.6 reported

   76 people1 study

   • Children who cannot make their own IGF-1 grew much faster on the replacement, and kept growing for years. 76 children were treated for up to twelve years with shots under the skin twice a day. Growth went from under three centimetres a year to eight in the first year, and stayed above where it started for up to eight...

     Journal of Clinical Endocrinology and Metabolism, 2007 · 76 people

9. 09MK-677Small moleculeLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 65 people given it.11 reported

   65 people1 study1 found nothing

   • found nothingIt shifted muscle and fat, and it did not make anyone stronger or more able. 65 adults aged 60 to 81 took MK-677 or a dummy pill daily for up to two years. Growth hormone and IGF-1 climbed back to young-adult levels. Lean tissue rose about 1.1 kg while the dummy group lost about half a kilo. Strength and everyday...

     Annals of Internal Medicine, 2008 · 65 people

10. 10MK-677 with ipamorelinBlendModerate. At least one finished study in people, and at least 100 people who took it. 2 completed trials, 182 people given it.7 reported

    65 people1 study

    • MK-677 worked in the longest study any of these drugs has had, and the gains were modest. 65 healthy adults aged 60 to 81 took a 25 mg pill or a dummy pill every day for two years. Nobody knew which they had. Growth hormone and IGF-1 climbed back into the range of a healthy young adult, with no serious harms. Lean...

      Annals of Internal Medicine, 2008 · 65 people

11. 11ForskolinSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 53 people given it.5 reported

    53 people2 studies1 found nothing

    • Body fat fell and testosterone rose, in thirty overweight men. The men all had a body mass index of 26 or above and took 250 mg of a 10 percent forskolin extract twice a day, or a dummy, decided by chance, for 12 weeks. Scans showed body fat percentage and fat mass dropped against the dummy group. Bone mass changed...

      Obesity Research, 2005 · 30 people

    • found nothingThe same supplement was tested in women and it did not work. 23 mildly overweight women took a 10 percent Coleus forskohlii extract twice a day or a dummy for 12 weeks, seven on the extract. Fat mass, lean mass and body fat percentage came out the same in both groups. Slight leanings toward less weight gain were too...

      Journal of the International Society of Sports Nutrition, 2005 · 23 people

12. 12SupaglutideBiologicModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 190 people given it.

    50 people1 study

    • The entire published obesity record for this drug is fifty people. They were spread across five doses and a dummy, starting at an average weight of 92.9 kg. Weight fell 7.16 percent against 0.86 percent on the dummy, and 82.5 percent of treated people lost at least a twentieth of their body weight, against nobody on...

      Diabetes, Obesity and Metabolism, 2026 · 50 people

13. 13ACE-031BiologicLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 48 people given it.5 reported

    48 people2 studies

    • One dose of ACE-031 added measurable muscle to healthy women within a month. Forty-eight women past menopause each received a single injection at one of several dose levels. At the highest dose, total muscle rose 3.3% and thigh muscle volume 5.1% by day 29. The drug lingers, taking ten to fifteen days for the body to...

      Muscle and Nerve, 2013 · 48 people

    • The trial was stopped early for safety, and it never showed a benefit. Boys with Duchenne muscular dystrophy were given ACE-031 or a dummy injection. After the second dose level, the study was halted because boys were getting nosebleeds and small spidery blood vessels in the skin. Walking distance and muscle mass...

      Muscle and Nerve, 2017 · number of people not given

14. 14L-leucineSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 30 people given it.3 reported

    30 people1 study1 found nothing

    • found nothingThree months of leucine did nothing at all for muscle in healthy older men. 30 men averaging 71 took 2.5 g of leucine with each main meal, 7.5 g a day, or a dummy, decided by chance. Scans of muscle size showed no change in either group. Strength on a one-lift maximum did not change either. Insulin sensitivity,...

      American Journal of Clinical Nutrition, 2009 · 30 people

15. 15SomatropinBiologicLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 84 people given it.9 reported

    24 people1 study1 found nothing

    • found nothingGrowth hormone changed what the body was made of without changing what the scales said. Twenty four adults whose bodies made too little growth hormone took it for six months, against others given a dummy version. They gained about 5.5 kg of muscle and lost about 5.7 kg of fat. Total weight barely moved, because the...

      New England Journal of Medicine, 1989 · 24 people

16. 16SermorelinPeptideModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 139 people given it.8 reported

    19 people1 study1 found nothing

    • found nothingThe hormone response faded while the injections carried on. Nineteen adults aged 55 to 71 injected salt water nightly for a month, then a sermorelin-like peptide for four more months. Growth hormone and its main blood marker rose within two weeks, stayed up for three months, then drifted back to where they started...

      Journal of Clinical Endocrinology and Metabolism, 1997 · 19 people

17. 17Ursolic acidSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 16 people given it.6 reported

    16 people1 study1 found nothing

    • found nothingThe entire human record for ursolic acid is sixteen men. 16 healthy men averaging 29 did eight weeks of weight training, seven on training alone and nine also taking ursolic acid capsules three times a day. Body fat percentage fell in the supplemented group. Body weight, body mass index, muscle mass, blood sugar and...

      Korean Journal of Physiology and Pharmacology, 2014 · 16 people

18. 18ClenbuterolSmall moleculeLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 11 people given it.5 reported

    18 people2 studies2 found nothing

    • found nothingClenbuterol does build muscle in people, and it wrecks your fitness while it does. 11 healthy young men took the drug for two weeks and a dummy for two weeks, in turn, with three weeks between. Lean mass rose by just under a kilogram. Fat mass did not move at all, which matters because fat loss is why most people buy...

      The Journal of Physiology, 2025 · 11 people

    • found nothingClenbuterol built leg muscle in heart failure patients and did nothing for their hearts. 7 people supported by a mechanical heart pump took rising oral doses for three months, up to a very high daily amount. Body weight and lean mass rose, and thigh strength improved from about 37 to about 46 kilograms of force. The...

      The Journal of Heart and Lung Transplantation, 2006 · 7 people

19. 19MyostatinBiologicModerate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 188 people given it.

    number of people not given2 studies1 found nothing

    • found nothingA drug that blocked myostatin alone failed in boys with Duchenne muscular dystrophy. Boys got the antibody or a dummy. After 49 weeks, the time to climb four stairs differed by a quarter of a second, which is nothing. No other measure of how the boys were doing separated the two groups. Gains in muscle size did not...

      Neuromuscular Disorders, 2020 · number of people not given

    • Blocking the receptor, not the hormone, caused big changes in body makeup. Adults with type 2 diabetes and obesity took bimagrumab or a dummy for 48 weeks. Fat fell by about a fifth, 7.5 kg, against almost nothing on the dummy. Muscle rose by 1.7 kg, waists shrank 9 cm, and average blood sugar fell by three quarters...

      JAMA Network Open, 2021 · number of people not given

20. 20RapamycinSmall moleculeLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 25 people given it.8 reported

    number of people not given1 study

    • Nearly a year of low dose rapamycin proved reasonably safe in ordinary ageing adults. Safety was the main thing the trial was built to check, and it checked out. Muscle mass and pain improved in women on the higher dose, which was one finding among many measures and needs repeating before anyone leans on it. Safe to...

      Aging, 2025 · number of people not given

21. 21DomagrozumabBiologicLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.

    number of people not given1 study1 found nothing

    • found nothingA second myostatin blocker was tested properly in boys with Duchenne and it failed. 120 boys aged six to fifteen were split by chance across three doses or a dummy injection, for nearly two years. The thing the trial was built to measure was how fast they climbed four stairs. The two groups came out the same. No other...

      Neuromuscular Disorders, 2020 · number of people not given

22. 22ApitegromabBiologicPreliminary. Studied in people, but no published study has had people take it. 2 human studies where nobody was given it.1 reported

    number of people not given1 study

    • Adding this antibody to tirzepatide protected about half the muscle people would otherwise have lost. It also changed what came off: 85% of the lost weight was fat, against about 70% on tirzepatide alone. Muscle loss is the main worry with these weight drugs, so this speaks straight to it. The trial was mid-stage and...

      Scholar Rock press release, 2025 · number of people not given

23. 23TrevogrumabBiologicLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.3 reported

    number of people not given1 study

    • Blocking two muscle brakes at once protected most of the muscle people lose on semaglutide. With all three drugs, about 81% of the muscle normally lost was kept, and people lost about 27% more fat than on semaglutide alone. Two drugs instead of three kept about half. These are company-reported figures from a mid-stage...

      Regeneron press release, 2025 · number of people not given

24. 24Collagen peptidesSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 69 people given it.4 reported

    number of people not given1 study

    • Put side by side with whey, collagen did not build muscle. Healthy older women were given the same amount of protein as either whey or collagen, with and without a workout. Whey switched muscle building on, both straight after the dose and over the longer run. Collagen did not, even when the researchers matched...

      American Journal of Clinical Nutrition, 2020 · number of people not given