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No match scores

Peptide finder

Pick what you want to change. See every compound measured for it in people, most people first. Each one shows what the study found, and the failures are counted.

Plate 11

Goal map

Find by outcome

Fat lossRecoverySleepSkinLongevityThe record

36

Goal pages

1

Record

Pick your goal. What was measured opens up, including the gaps.

The short answer

Pick what you want to change. See every compound measured for it in people, most people first. Each one shows what the study found, and the failures are counted. 70 of 453 compounds here have no study in people of any kind.

Compounds
453
No study in people
70

How this ranks

No match scores

Other tools print a match percentage. Nobody measured those numbers. This page shows how many people each goal was measured in, and names the goals nobody has measured in a person.

A thin record in people is usually about who pays for trials. It is not a verdict on the compound.

What users report sits next to the trial count. It is never added into it.

What are you trying to change?

Pick as many as you like. The number on each one is how many people it has been measured in across the whole archive. So you can see where the evidence is before you choose.

Somebody handed you a stack. What is actually known about it?

Add what you are looking at. You get every goal those compounds have been measured for in people. Then you get the longer list of goals they have not.

Skin, wrinkles and elasticity

Does it actually do anything for skin?

Skin trials are usually small, short, and funded by whoever sells the product. That is not a reason to ignore them, it is a reason to read who paid.

975 people · 13 studies in people · 8 compounds

  1. 01MelittinPeptideModerate. At least one finished study in people, and at least 100 people who took it. 5 completed trials, 658 people given it.4 reported
    538 people1 study
    • This tested whole bee venom, not melittin. Five hundred and thirty eight people with knee arthritis got weekly skin injections of venom, or of a control substance, for twelve weeks. Pain and physical function improved more on the venom. The gains were modest in size. Reactions where the needle went in were uncommon....

      Journal of Alternative and Complementary Medicine, 2019 · 538 people

  2. 02ArgirelinePeptideModerate. At least one finished study in people, and at least 100 people who took it. 4 completed trials, 155 people given it.7 reported
    150 people5 studies1 found nothing
    • In a short trial the cream beat a dummy cream, mostly on what people said about their own faces. Sixty people used one or the other for four weeks. Just under half the treated group counted as responding, against none of the dummy group. Measured skin roughness moved the same way. A gap that wide is unusual in...

      American Journal of Clinical Dermatology, 2013 · 60 people

    • Wrinkles improved, and every author works for L'Oreal. Two studies were run, 50 people for still wrinkles and 42 for the wrinkles that appear when the face moves. After twelve weeks the still-wrinkle scores improved a lot and the moving-wrinkle scores improved a little. Nothing here can be credited to acetyl...

      International Journal of Cosmetic Science, 2026 · 50 people

    • A small three-way test in which this peptide came last. 21 Indonesian women aged 26 to 55 were sorted by chance into three creams: acetylhexapeptide-3, palmitoyl pentapeptide-4, or a dummy. That is about seven women per group. Over eight weeks, instruments and a wrinkle scale put palmitoyl pentapeptide-4 ahead of both...

      Journal of Clinical and Aesthetic Dermatology, 2023 · 21 people

  3. 03MatrixylPeptideModerate. At least one finished study in people, and at least 100 people who took it. 2 completed trials, 114 people given it.7 reported
    93 people1 study
    • This is the best designed trial any of these cosmetic peptides has, and the peptide won. Ninety three women put the active cream on one side of the face and a plain moisturiser on the other for twelve weeks. Each woman was her own comparison, which removes most of the ways skin studies mislead. Wrinkles and fine lines...

      International Journal of Cosmetic Science, 2005 · 93 people

  4. 04Collagen peptidesSupplementLimited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 69 people given it.4 reported
    69 people1 study
    • This is the skin study the ads lean on. 69 women aged 35 to 55 took 2.5 grams or 5 grams of a branded collagen peptide, or a dummy pill, for 8 weeks. Skin stretch, the measure they named first, improved against the dummy in both dose groups. Moisture and water loss did not clearly change. Some authors have ties to the...

      Skin Pharmacology and Physiology, 2014 · 69 people

  5. 05Argireline with Matrixyl and SNAP-8BlendLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 60 people given it.6 reported
    60 people1 study1 found nothing
    • found nothingArgireline cream reduced wrinkle roughness in a small, short, four week test. 60 people were put by chance, three to one, on argireline or a dummy cream, twice a day around the eyes. Judges scoring by eye rated about half the argireline group as improved overall, and the dummy group not at all. Silicone moulds of the...

      American Journal of Clinical Dermatology, 2013 · 60 people

  6. 06IdebenoneSupplementModerate. At least one finished study in people, and at least 100 people who took it. 5 completed trials, 732 people given it.
    41 people1 study
    • A skin cream study with no honest comparison. 41 women aged 30 to 65 with sun damaged skin used an idebenone lotion twice a day for six weeks. Graders scored the stronger version as cutting roughness and dryness by about a quarter, cutting fine lines by about a third, and raising hydration by a third. Nobody used the...

      Journal of Cosmetic Dermatology, 2005 · 41 people

  7. 07SNAP-8PeptideLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 24 people given it.7 reported
    24 people2 studies
    • One eye got the active patch and the other got a plain one, which is a fair way to test a face. Twenty four healthy people wore them for four weeks. The treated side showed better wrinkle improvement, held water in the skin better and was more elastic, with no side effects reported. As in the earlier patch study, this...

      Annals of Dermatology, 2024 · 24 people

    • A patch containing this peptide reduced fine lines, but the peptide cannot take the credit. People used it for twelve weeks and finished with about a quarter fewer fine lines. The patch carried several active ingredients at once, along with hyaluronic acid and the tiny needles that deliver it. Nothing in the design...

      Journal of Cosmetic Dermatology, 2020 · number of people not given

  8. 08SetmelanotidePeptideLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 38 people given it.4 reported
    number of people not given1 study
    • In rare genetic forms of obesity most patients lost serious weight, and there was nobody to compare them against. After about a year, 8 of 10 people with one gene fault and 5 of 11 with the other had lost at least a tenth of their body weight. Reported hunger fell by roughly a third in one group and nearly half in the...

      The Lancet Diabetes & Endocrinology, 2020 · number of people not given

  9. 09Ginsenoside Rg3SupplementLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 24 people given it.
    number of people not given0 studies
    • In a dish. The 20(S) form brought worn-out human skin cells back to a younger state by restoring their energy supply and changing growth and repair signals. The 20(R) form did not. This is bringing worn-out cells back, not clearing them.

      Journal of Ginseng Research, 2020 · number of people not given

  10. 10TB-500PeptidePreliminary. Studied in people, but no published study has had people take it. 1 registered with no result.9 reported
    number of people not given0 studies
    • 11PT-141PeptideStrong. At least two finished studies in people, and at least 1,000 people who took it. 4 completed trials, 2,355 people given it.9 reported
      number of people not given0 studies
      • 12GHK-Cu with zinc thymulinBlendLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 13 people given it.7 reported
        number of people not given0 studies
        • 13AHK-Cu with GHK-CuBlendLimited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 13 people given it.5 reported
          number of people not given0 studies

          How this is counted

          Studies in people only. Animal and lab work never goes into this ranking, because your question was about a person.

          A compound is listed for a goal only when a study on its own page names that goal and reports a result for it. Just naming it is not enough. Say a paper measures testosterone but reports a result about something else. That does not count as testosterone evidence. This tool made that mistake on its first run, and it no longer does.

          People counts come from the study lines themselves, and when in doubt they count low. If a line gives no number, the study still counts as a study but adds nobody to the people count. Counts are never added up across compounds, because the same person can be in more than one trial.

          The order is by how many people were measured. That is a fact about the evidence, not a judgement about the compound. It is the only order this site will defend. A compound at the top of a list is the most studied. That is not the same as the best.

          Nothing here is advice. Nothing here tells you to take anything.

          How we grade evidence