What does MOTS-c stand for?
MOTS-c stands for Mitochondrial ORF of the 12S rRNA type-c. It is a 16-amino-acid peptide made from the DNA inside mitochondria (the power plants of cells), with a molecular weight of about 2,174 daltons. The letters name where its code sits in the mitochondria's DNA. They are not a brand and not a measured fat-loss result. The evidence in people on this site only watched people: blood levels, a mitochondrial gene variant in 27,527 people, and a rise in the body's own MOTS-c with exercise. A mid-stage study is still signing people up (NCT07505745). Nobody on this site has yet published a study of giving MOTS-c to a person as a finished drug.
Studies in people from the compound pages this answer belongs to
- MOTS-c
- A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c 2021 PMID 33468709
- Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition 2020 PMID 32182209
- Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction 2018 PMID 29242099
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of further names and published absences. Leftover harvested questions after the first two absence sets: more brand versus molecule names, side effects the citations did not count, compounding formulas this catalogue does not hold, national FDA and Australia fields, trial windows rather than an onset clock, named combinations with no interaction table, and oral routes that have not been studied.