Should ipamorelin be cycled?

Published human trials do not establish an on/off schedule for ipamorelin. This site's review found one human citation for it, and that study does not compare a cycle length against continuous use. It acts at the same ghrelin receptor family where daily GHRP-2 reduced peak growth hormone over five days in nine healthy men, so a tolerance mechanism exists in that family, but nobody has tested an ipamorelin pause calendar. Community protocols are unverified. This site does not invent a schedule. Full detail at /cycling.

Full cycling page: what is measured versus assumed

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of cycling and clearance. Whether peptides need a break, what a half-life actually tells you, and where a real cycling mechanism has been measured. Full detail at /cycling.