Should retatrutide be cycled?

Retatrutide is investigational and studied in its Phase 3 program as continuous weekly dosing, the same regimen used for the approved GLP-1 drugs it is related to, not as a cycle. No trial has tested stopping and restarting it on a schedule.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of cycling and clearance. Whether peptides need a break, what a half-life actually tells you, and where a real cycling mechanism has been measured. Full detail at /cycling.