How does selank work?
Selank is a lab-made copy of tuftsin, a small immune peptide. This site's profile says it acts on the brain's calming (GABA) and mood chemical systems, and affects how natural painkillers (enkephalins) break down and how much BDNF is made. Together, that eases anxiety. The body clears it quickly, in minutes, and it is used as a nose spray. Its molecular weight is 751.9 daltons. The one study in people on that page is a 62-patient Russian study in people with anxiety disorder or nervous exhaustion (neurasthenia). 30 got Selank and 32 got medazepam, an older anti-anxiety drug. Both eased anxiety about equally, and Selank also seemed to fight tiredness and give a mild lift. There was no dummy-pill group. It is approved in Russia and not FDA approved. In rats and mice, animal studies on that page report anti-stress effects of Selank and related tuftsin-family peptides. Those animal findings do not transfer into a counted Western replication. This FAQ does not invent a dose. Full record at /compounds/selank.
Studies in people from the compound pages this answer belongs to
- Selank
- Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia 2008 PMID 18454096
- [A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders]. 2014 PMID 25176261
- [Optimization of the treatment of anxiety disorders with selank]. 2015 PMID 26356395
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of cognitive and mood peptides. Selank, semax, cerebrolysin, and other nootropic and CNS peptides.