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Gut health

What has been measured for gut health?

The gut lining, gut growth, and the compounds used when part of the bowel has been removed (short bowel syndrome). A small area with a couple of truly approved drugs in it.

41 compounds studied for this · 6 with a completed trial of a hundred people or more · 9 with no study in people at all

What has actually been measured here

This page lists the compounds studied for gut health. These pages work the other way round. They take one goal at a time and list every compound by how many people it was measured in, most first. Each shows what the study found, and the trials that found nothing are counted.

Or open all 3 of these together in the finder.

Strong and Moderate 6

At least one finished trial that gave the compound to a hundred people or more. That tells you how much has been measured. It does not tell you whether it will work for you. The math sits under every band.

Larazotide

Moderate. At least one finished study in people, and at least 100 people who took it. 2 completed trials, 526 people given it.
3 cited

A gut barrier peptide for celiac disease that is still being tested. It reached a large final-stage study, but the compa...

PeptideHealing & Recovery

Berberine

Moderate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 186 people given it.4 reported
3 cited

Across 46 studies, berberine lowered average blood sugar (HbA1c) by 0.73 points. In a small head-to-head test, it lowere...

SupplementMetabolic

Glepaglutide

Moderate. At least one finished study in people, and at least 100 people who took it. 3 completed trials, 230 people given it.
6 cited

A long-lasting copy of GLP-2, a gut hormone, for people whose short bowel means they need feeding by drip. In a 106 pers...

PeptideMetabolic

Plecanatide

Strong. At least two finished studies in people, and at least 1,000 people who took it. 2 completed trials, 1,337 people given it.3 reported
2 cited

A constipation pill approved in 2017, for long-term constipation with no known cause and for IBS with constipation. It i...

PeptideHealing & Recovery

Thymosin alpha-1 with KPV and LL-37

Strong. At least two finished studies in people, and at least 1,000 people who took it. 3 completed trials, 1,140 people given it.6 reported
3 cited

A three-peptide immune blend from the clinic end of the market. The ingredient with the biggest study, thymosin alpha-1,...

BlendImmune

Taspoglutide

Strong. At least two finished studies in people, and at least 1,000 people who took it. 3 completed trials, 2,181 people given it.
7 cited

A once-a-week GLP-1 shot that lowered average blood sugar (HbA1c) more than exenatide and sitagliptin in large final-sta...

PeptideMetabolic

Limited and Preliminary 26

Someone has been given it and a result was published, but in fewer than a hundred people. Or the studies in people only watched and never gave anybody anything. The math on each card says exactly how thin.

BPC-157

Limited. People have taken it in a published study, but fewer than 100 of them. 3 completed trials, 31 people given it.10 reported
7 cited

A lab-made piece of a stomach protein. It has lots of animal studies on tendon, muscle and gut healing. In people there...

PeptideHealing & Recovery

Teduglutide

Limited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 83 people given it.4 reported
3 cited

An FDA-approved shot that helps the gut grow in short bowel syndrome, so people need less feeding through a vein.

PeptideMetabolic

Apraglutide

Limited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, none stating how many people.
2 cited

A once a week version of GLP-2 for short bowel syndrome, where the approved drug, teduglutide, needs a daily shot. In sm...

PeptideHealing & Recovery

Linaclotide

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.3 reported
1 cited

In 839 adults with irritable bowel syndrome and constipation, 60 percent had less belly pain on it, against 49 percent o...

PeptideHealing & Recovery

Acarbose

Preliminary. Studied in people, but no published study has had people take it. 2 human studies where nobody was given it.4 reported
2 cited

An old, cheap diabetes pill that slows how fast starch turns into sugar. In people, a large heart study found no heart b...

Small moleculeLongevity

Dapiglutide

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 54 people given it.
2 cited

The only drug in weight-loss testing that pairs GLP-1 with GLP-2. Its first test missed. In 54 people over 12 weeks, it...

PeptideMetabolic

PL8177

Preliminary. Studied in people, but no published study has had people take it. 2 human studies where nobody was given it.2 reported
2 cited

Palatin's peptide pill that switches on MC1R, for ulcerative colitis. In a small mid-stage study, 33 percent went into r...

PeptideMelanocortin

Inulin

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 39 people given it.6 reported
1 cited

It did not help mice live longer, in either sex, in the same test where extra glycine gave a 4 to 6 percent gain. In a r...

SupplementMetabolic

Semaglutide with BPC-157

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.7 reported
1 cited

An approved drug with a 14.9% weight loss result, paired with a peptide the FDA looked at in 2026 and found no good huma...

BlendMetabolic

Neurotensin

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 6 people given it.
2 cited

Neurotensin is a small 13-building-block peptide your body makes. It eases pain in rodents. No human study has tested pa...

PeptideNootropic & CNS

ARD-101

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 20 people given it.3 reported
4 cited

It made adults less hungry by switching on bitter taste receptors in the gut. Both of its final-stage studies, in a rare...

Small moleculeMetabolic

Oxyntomodulin

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 13 people given it.
4 cited

Oxyntomodulin is glucagon with eight extra building blocks on the end. That tail lets it weakly switch on two hormone re...

PeptideMetabolic

KLOW blend

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 13 people given it.11 reported
2 cited

KLOW is a seller's mix of four peptides in one vial, usually 50 mg GHK-Cu plus 10 mg each of KPV, BPC-157 and TB-500. It...

BlendHealing & Recovery

Quad healing blend

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, 13 people given it.8 reported
1 cited

The same four peptides as KLOW, mixed in very different amounts. It is usually 5 mg TB-500, 5 mg BPC-157, 10 mg KPV and...

BlendHealing & Recovery

Tirzepatide with BPC-157

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.7 reported
1 cited

The same pairing idea as the semaglutide version. One side has a bigger weight loss effect. The other side is just as em...

BlendMetabolic

Zinc-L-carnosine

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.2 reported
1 cited

In a final-stage trial in women having radiotherapy for breast cancer, it prevented trouble swallowing. It is a mix of z...

SupplementHealing & Recovery

GIP

Limited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 10 people given it.2 reported
6 cited

GIP is one of two gut hormones that tell your pancreas to release insulin after a meal. It is the G in tirzepatide and t...

PeptideMetabolic

(R/S)-1,3-Butanediol

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.2 reported
3 cited

In people, it raises blood ketones for a few hours. In 9 cyclists, it gave 5 of them moderate to severe gut problems and...

SupplementLongevity

Peptide YY

Limited. People have taken it in a published study, but fewer than 100 of them. 3 completed trials, 12 people given it.3 reported
3 cited

Peptide YY is a gut hormone your body releases after meals, alongside GLP-1. Given by drip to 12 lean and 12 obese peopl...

PeptideMetabolic

Urolithin A

Limited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, none stating how many people.4 reported
3 cited

A compound your gut makes from pomegranates and berries. In older adults it helped muscle stamina and strength on some t...

SupplementMuscle & Performance

BI 3034701

Preliminary. Studied in people, but no published study has had people take it. 2 human studies where nobody was given it.1 reported
2 cited

Boehringer Ingelheim's drug that works on three signals: GLP-1, GIP and NPY2, a fullness signal from the gut. It started...

PeptideMetabolic

GLP-1

Limited. People have taken it in a published study, but fewer than 100 of them. 2 completed trials, 8 people given it.1 reported
2 cited

The natural gut hormone behind the whole GLP-1 drug family. You make it after you eat, and it raises insulin and cuts ap...

PeptideMetabolic

VIP

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.2 reported
2 cited

A signalling peptide with wide effects on the immune system, swelling and blood flow. It has been studied as a nose spra...

PeptideHealing & Recovery

HEC88473

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.1 reported
1 cited

The only GLP-1 pairing on this site that is not with another gut hormone. It pairs GLP-1 with FGF21, a liver hormone, to...

BiologicMetabolic

Lanreotide

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.4 reported
1 cited

In people with advanced neuroendocrine tumours of the gut and pancreas, it kept tumours from growing for longer. At two...

PeptideHormone

Urolithin B

Limited. People have taken it in a published study, but fewer than 100 of them. 1 completed trial, none stating how many people.
1 cited

Sold on the good name of urolithin A, which has human studies. Urolithin B has none. Its muscle result comes from muscle...

SupplementMuscle & Performance

Animal or lab only, and nothing measured 9

Studied in animals or in cells in a dish, or studied in people for something else entirely. Listed, not hidden, because knowing a thing has not been tested in a person is the useful part.

KPV

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 2 animal studies, no human study.6 reported
none cited

A tiny peptide of three amino acids, cut from the hormone alpha-MSH. It calms swelling and is studied for gut and skin i...

PeptideHealing & Recovery

BPC-157 with KPV

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 1 animal study, no human study.7 reported
none cited

Two peptides sold together for gut problems, most often 10 mg of each in a 20 mg vial. Nobody has ever studied the pair....

BlendHealing & Recovery

GLP-2

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 1 animal study, no human study.1 reported
none cited

A natural gut hormone that helps the gut lining grow and heal. It is the model for the drug teduglutide.

PeptideMetabolic

Ovagen

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 1 animal study, 1 lab study, no human study.7 reported
none cited

Sold as a liver and gut peptide, with the sequence Glu-Asp-Leu. A PubMed search for Ovagen finds 34 papers, and none is...

PeptideAnti-aging

Deadpool blend

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 1 animal study, 1 lab study, no human study.7 reported
none cited

A vial of three repair peptides, most often 10 mg each of BPC-157, TB-500 and KPV. It is sold as KLOW without the copper...

BlendHealing & Recovery

Pentadeca Arginate

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 1 animal study, no human study.8 reported
none cited

Pentadeca arginate is BPC-157 with a different salt. The 15 building blocks are the same. It was made to get around comp...

PeptideHealing & Recovery

Chonluten

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 2 lab studies, no human study.2 reported
none cited

Chonluten is a three building block peptide from Khavinson's institute, sold for lung and gut lining health. The evidenc...

PeptideImmune

GB-115

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 2 animal studies, no human study.2 reported
none cited

GB-115 is a Russian anti-anxiety pill made of two building blocks. It works on a gut and brain signal called CCK. Wester...

PeptideNootropic & CNS

Livagen

Animal or lab only. Only animal or lab studies on this page. No study in people yet. 2 lab studies, no human study.4 reported
none cited

Livagen is a four building block peptide from Khavinson's institute, sold for liver and gut health. All the work so far...

PeptideLongevity

Reading on this goal

Peptides for Joint Pain: BPC-157, TB-500, Lorecivivint, Pentosan and Collagen Peptides, Evidence Tiered

What studies in people say about joint pain treatments: hyaluronic acid shots (89 studies, tiny effect), lorecivivint (waiting on the FDA since January 2026 after two big studies failed on pain), collagen peptides (three small studies), pentosan polysulfate (a 538-person study reporting in 2027), and BPC-157 and TB-500, whose human records sit outside the joint entirely. Plain English.

Peptides for Gut Health: BPC-157, KPV and Larazotide Ranked by Human Evidence

Five peptides sold or studied for the gut, sorted by what has actually been tested in people: larazotide (a good mid-sized study, then a big study stopped in 2022 because it wasn't working), teduglutide (approved), BPC-157 (three small reports in people, none about the gut), KPV (never tested in people) and pentadeca arginate (no studies at all), plus what the July 2026 FDA panel votes did and did not decide. Plain English.

Peptide Side Effects by Class: What Is Documented, What Is Anecdotal

A group-by-group table that separates side effects counted in studies and on FDA labels (GLP-1 drugs, bremelanotide, MK-677, elamipretide) from the stories that fill forums about BPC-157, TB-500, copper peptides and brain peptides. Plain English.

How to Read a Peptide Certificate of Analysis: HPLC Purity, Mass Spec Identity, Endotoxin, and Janoshik Verification

What each line on a peptide lab certificate means, what a purity number does and does not tell you, how to check a Janoshik report, and the warning signs the FDA's own 2026 review found in products on the market. Plain English. No seller recommendations.

What the number counts, exactly

The number on each card is how many sources on that compound’s page are studies in people. It is counted the same simple way for all 453 compounds. You can check any of it by opening the profile and reading the list of sources. That is the whole point of showing a number at all.

It counts what we cite. It does not claim how much research exists. A compound with three studies in people here may have thirty in print, and the honest thing to say is that we have read and listed three. It is also not a quality score. Three small, loose studies count the same as three careful ones. So the groups tell you how much was measured in people, and the profile page tells you how well.

Other goals