How does melanotan 1 work?
Melanotan I, also called afamelanotide and sold as Scenesse, switches on the melanocortin-1 receptor. That makes the skin produce more dark pigment (eumelanin), which protects it from light. This site's profile says the body clears half of it in about 30 minutes. The approved product is a slow-release implant. Its molecular weight is 1,646.9 daltons. Two studies, 94 people in the United States and 74 in Europe, found people with afamelanotide implants could spend longer in the sun without pain (US middle value 69.4 versus 40.8 hours; Europe 6.0 versus 0.8 hours), with fewer skin reactions to light. They were adults with erythropoietic protoporphyria, a rare disorder that makes skin extremely sensitive to light. The FDA approved it in October 2019, as a 16 mg implant, for that rare disorder in adults with a history of light reactions, not for cosmetic tanning. A research-chemical vial labeled melanotan 1 is not Scenesse. This FAQ does not invent a dose. Full record at /compounds/melanotan-1.
Studies in people from the compound pages this answer belongs to
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of sexual health and hormone peptides. PT-141, melanotan, oxytocin, gonadorelin, and kisspeptin-10.