Is kisspeptin-10 the same as kisspeptin-54?
No. They are different-length products of the same KISS1 gene. Kisspeptin-10 is the 10-amino-acid piece sold as a research chemical, with a molecular weight of about 1,302 daltons. Its own study in people measured LH and testosterone in healthy men. Kisspeptin-54 is the full 54-building-block product of the gene, also called metastin or KP-54, and has its own page. The IVF egg-trigger studies, the first drip study in people, and the brain scan study cited on the kisspeptin-10 page all used kisspeptin-54, not the piece. That page says those results should not be read as results for kisspeptin-10. Sharing a receptor family does not make them the same molecule. Full records at /compounds/kisspeptin-10 and /compounds/kisspeptin-54.
Studies in people from the compound pages this answer belongs to
- Kisspeptin-10
- Kisspeptin-54
- Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy 2015 PMID 26192876
- A second dose of kisspeptin-54 improves oocyte maturation in women at high risk of ovarian hyperstimulation syndrome: a Phase 2 randomized controlled trial 2017 PMID 28854728
- Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis 2009 PMID 19820030
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of sexual health and hormone peptides. PT-141, melanotan, oxytocin, gonadorelin, and kisspeptin-10.