Is melanotan 2 the same as setmelanotide?
No. They are different drugs that switch on melanocortin receptors. Melanotan II is unapproved and switches on both MC1R and MC4R, with a molecular weight of 1,024.2 daltons. It was studied for tanning and erections in studies of three and ten men, and Australia bans its supply. Setmelanotide switches on only MC4R. It is approved as Imcivree for rare obesity caused by genes, not for common obesity or tanning. 8 of 10 people with POMC deficiency and 5 of 11 with LEPR deficiency lost at least 10% of body weight at about one year. Sharing a receptor family does not make them the same molecule or the same approval, and it does not mean a tan. This site does not rank them. Full records at /compounds/melanotan-2 and /compounds/setmelanotide.
Studies in people from the compound pages this answer belongs to
- Melanotan II
- Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study 1996 PMID 8637402
- Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study 1998 PMID 9679884
- Alpha-melanocyte-stimulating hormone-induced eruptive nevi 2009 PMID 19380666
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of sexual health and hormone peptides. PT-141, melanotan, oxytocin, gonadorelin, and kisspeptin-10.