What is gonadorelin used for?
Gonadorelin is a lab-made copy of gonadotropin releasing hormone (GnRH), the brain signal that starts the sex hormone chain. It was once FDA approved for testing and for fertility treatment, but those approvals have mostly been dropped. Today it is mainly used off-label, and through compounding, to help keep the testicles working during testosterone replacement. It does that by prompting the body's own hormone chain, instead of replacing testosterone directly.
Studies in people from the compound pages this answer belongs to
- Gonadorelin
- Induction of puberty in men by long-term pulsatile administration of low-dose gonadotropin-releasing hormone 1982 PMID 6813732
- Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism. 2002 PMID 12213860
- The Pulsatile Gonadorelin Pump Induces Earlier Spermatogenesis Than Cyclical Gonadotropin Therapy in Congenital Hypogonadotropic Hypogonadism Men. 2019 PMID 30569789
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of sexual health and hormone peptides. PT-141, melanotan, oxytocin, gonadorelin, and kisspeptin-10.