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Is metastin the same as kisspeptin-54?

Yes. Metastin is an alias listed on this site's kisspeptin-54 profile, alongside KP-54. It names the same 54-residue KISS1 gene product, roughly 6 kilodaltons, that binds KISS1R on GnRH neurons. The IVF trigger programme at Imperial used kisspeptin-54: oocyte maturation in 95% of 60 women at high risk of ovarian hyperstimulation syndrome, with no moderate, severe, or critical cases. Metastin is not kisspeptin-10, the 10-amino-acid fragment sold as a research chemical. The names are aliases of the longer peptide, not a US approval. Full record at /compounds/kisspeptin-54.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of sexual health and hormone peptides. PT-141, melanotan, oxytocin, gonadorelin, and kisspeptin-10.

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