Can MOTS-c cause headaches?

This site's MOTS-c citations do not measure headache. Human evidence on this site is observational: circulating levels, a mitochondrial DNA variant in 27,527 people, and an exercise-related rise in endogenous MOTS-c, plus a Phase 2a trial still recruiting (NCT07505745). Nobody on this site has yet published a trial of giving MOTS-c to a person as a finished drug, so there is no administration-trial adverse-event table to quote. This FAQ does not invent a headache rate from observational circulating levels.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.