How does thymogen work?

Thymogen is a synthetic dipeptide of glutamic acid and tryptophan, Glu-Trp. This site's profile proposes that it modulates T-cell function as a minimal active fragment of thymic peptides such as Thymalin. Half-life is listed as short. Molecular weight is 333.3 daltons. The one human citation is a 1996 Russian clinical report in type 1 diabetes describing reversed signs of secondary immunodeficiency via T-lymphocyte differentiation; everybody got the drug, and there was no comparison group. A 2024 review pairs it with its D-isomer thymodepressin as opposite-acting immunomodulators. It is used in Russia and is not FDA approved. An uncontrolled report is not a counted immune-restoration trial. This FAQ does not invent a human mechanism. Full record at /compounds/thymogen.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.