Is humanin the same kind of peptide as MOTS-c?
They come from the same place. Both are made from the DNA inside mitochondria, not the DNA in the cell's center. And both have data in people that links their natural levels to aging and metabolic health, not data from giving them as drugs. Humanin's record in people centers on families of centenarians (very long-lived people) and on heart risk. MOTS-c's centers on a gene variant and on exercise. Neither has a finished, published study of giving it to people yet.
Studies in people from the compound pages this answer belongs to
- Humanin
- Humanin detected in skeletal muscles of MELAS patients: a possible new therapeutic agent 2005 PMID 15759134
- Humanin: a mitochondrial signaling peptide as a biomarker for impaired fasting glucose-related oxidative stress 2016 PMID 27173674
- Unbalanced circulating Humanin levels and cardiovascular risk in chronic hemodialysis patients: a pilot, prospective study 2024 PMID 39102184
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.