Does MOTS-c help with weight loss?
This site's review found 13 studies for MOTS-c, 8 of them in people, covering more than 27,000 people. But that evidence only watched people, it did not give them the peptide: gene variant studies, blood level measures across age and metabolic disease, and a response to exercise. No study has yet given MOTS-c to a person and measured weight change. That is exactly what its first careful mid-stage study, now signing people up, is built to find out.
Studies in people from the compound pages this answer belongs to
- MOTS-c
- A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c 2021 PMID 33468709
- Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition 2020 PMID 32182209
- Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction 2018 PMID 29242099
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.