How does MOTS-c work?

MOTS-c is encoded within mitochondrial DNA and is thought to act on cellular energy metabolism and insulin sensitivity, based on its association with a common genetic variant, its response to exercise, and its changing levels across age and metabolic disease in observational human data. Whether administering it as a drug reproduces those associations is exactly what its first recruiting controlled trial is designed to test, not something the existing observational data can answer alone.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.