How does MOTS-c work?
MOTS-c is made from the DNA inside mitochondria (the power plants of cells). It is thought to act on how cells use energy and how well the body responds to insulin. That idea rests on data that watched people: its link to a common gene variant, its response to exercise, and how its levels change with age and metabolic disease. Whether giving it as a drug does the same thing is exactly what its first careful study, now signing people up, is built to test. The existing data cannot answer that alone.
Studies in people from the compound pages this answer belongs to
- MOTS-c
- A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c 2021 PMID 33468709
- Increased expression of the mitochondrial derived peptide, MOTS-c, in skeletal muscle of healthy aging men is associated with myofiber composition 2020 PMID 32182209
- Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction 2018 PMID 29242099
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.