Is Sirolimus the same as rapamycin?

Yes. Sirolimus is the generic name listed as another name on this site's rapamycin profile, along with Rapamune. It names the same mTOR blocker, with a molecular weight of 914.2 daltons. Rapamune is the FDA approved brand for preventing transplant rejection. Using it for longevity is off-label and still experimental. PEARL and the 25-person Kraig pilot are the aging-related record in people on that page, not a lifespan approval. The names are aliases of one molecule. This site does not rank brands. Full record at /compounds/rapamycin.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.