Is SS-31 the same as elamipretide?
Yes. SS-31 and MTP-131 are aliases on this site's elamipretide profile for the same peptide aimed at mitochondria, with a molecular weight of 639.8 daltons. It sticks to cardiolipin in the inner wall of mitochondria. The FDA approved name is elamipretide. The finished medicine is Forzinity, given fast-track (accelerated) approval on September 19, 2025, for Barth syndrome (a rare inherited disease) in patients who weigh 30 kg or more. A research-chemical vial labeled SS-31 is not that labeled product, and the approval does not cover longevity or tiredness. MMPOWER-3, a large final-stage study in 218 people with a muscle disease caused by faulty mitochondria, missed both of its main goals. The names are aliases of one molecule. Full record at /compounds/elamipretide.
Studies in people from the compound pages this answer belongs to
- Elamipretide
- Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy: The MMPOWER-3 Randomized Clinical Trial 2023 PMID 37268435
- Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER 2024 PMID 38602181
- ReCLAIM-2: A Randomized Phase II Clinical Trial Evaluating Elamipretide in Age-related Macular Degeneration, Geographic Atrophy Growth, Visual Function, and Ellipsoid Zone Preservation 2025 PMID 39605874
Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.
Part of immune and longevity peptides. Thymosin alpha-1, thymalin, epitalon, MOTS-c, humanin, and the bioregulator family.