How does BPC-157 work?

This site's BPC-157 profile states that no receptor or molecular target has been identified in people. FDA's 2026 evaluation gave that missing target as one reason it could not judge biological plausibility. Human mechanistic work on this site is limited to the observation that the peptide was not detectable in plasma after rectal dosing, and to a two-person pilot consistent with a plasma half-life under 30 minutes. FDA counted five human studies totaling fewer than 110 people, none by the subcutaneous or oral routes most buyers use. The animal literature describes angiogenesis, nitric oxide signaling, and growth hormone receptor expression in tendon fibroblasts. Those animal findings do not transfer into a counted human healing mechanism. This FAQ does not invent a target. Full record at /compounds/bpc-157.

Educational use only. This database summarizes published research and is not medical advice. Where a dose appears it is a record of what a trial or clinic ran, or what people describe doing, with its source attached. Nothing here is a recommendation for personal use.

Part of healing and recovery peptides. BPC-157, TB-500, GHK-Cu, and the tissue repair family, including what actually has human data.